(+)-alpha-santalene synthase ((2Z,6Z)-farnesyl diphosphate cyclizing)

{{Short description|Class of enzymes}}

{{Infobox enzyme

| Name = (+)-α-santalene synthase ((2Z,6Z)-farnesyl diphosphate cyclizing)

| EC_number = 4.2.3.50

| CAS_number =

| GO_code =

| image =

| width =

| caption =

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(+)-α-Santalene synthase ((2Z,6Z)-farnesyl diphosphate cyclizing) (EC 4.2.3.50, SBS) is an enzyme with systematic name (2Z,6Z)-farnesyl diphosphate lyase (cyclizing; (+)-α-santalene-forming).{{cite journal |vauthors=Sallaud C, Rontein D, Onillon S, Jabès F, Duffé P, Giacalone C, Thoraval S, Escoffier C, Herbette G, Leonhardt N, Causse M, Tissier A |title=A novel pathway for sesquiterpene biosynthesis from Z,Z-farnesyl pyrophosphate in the wild tomato Solanum habrochaites |journal=The Plant Cell |volume=21 |issue=1 |pages=301–17 |date=January 2009 |pmid=19155349 |doi=10.1105/tpc.107.057885 |pmc=2648096}} This enzyme catalyses the following chemical reaction

: (2Z,6Z)-farnesyl diphosphate $\backslash rightleftharpoons$ (+)-α-santalene + diphosphate

The enzyme synthesizes a mixture of sesquiterpenoids from (2Z,6Z)-farnesyl diphosphate.