:(+)-beta-caryophyllene synthase

{{Short description|Class of enzymes}}

{{Infobox enzyme

| Name = (+)-β-caryophyllene synthase

| EC_number = 4.2.3.89

| CAS_number =

| GO_code =

| image =

| width =

| caption =

}}

(+)-β-Caryophyllene synthase (EC 4.2.3.89, GcoA) is an enzyme with systematic name (2Z,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-β-caryophyllene-forming).{{cite journal | vauthors = Nakano C, Horinouchi S, Ohnishi Y | title = Characterization of a novel sesquiterpene cyclase involved in (+)-caryolan-1-ol biosynthesis in Streptomyces griseus | journal = The Journal of Biological Chemistry | volume = 286 | issue = 32 | pages = 27980–7 | date = August 2011 | pmid = 21693706 | doi = 10.1074/jbc.m111.265652 | pmc=3151043| doi-access = free }} This enzyme catalyses the following chemical reaction:

: (2E,6E)-farnesyl diphosphate $\backslash rightleftharpoons$ (+)-β-caryophyllene + diphosphate

This enzyme also converts the (+)-β-caryophyllene to (+)-caryolan-1-ol.