:(+)-delta-selinene synthase

{{Short description|Class of enzymes}}

{{Infobox enzyme

| Name = (+)-δ-selinene synthase

| EC_number = 4.2.3.76

| CAS_number =

| GO_code =

| image =

| width =

| caption =

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(+)-δ-Selinene synthase (EC 4.2.3.76) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((+)-δ-selinene-forming).{{cite journal | vauthors = Steele CL, Crock J, Bohlmann J, Croteau R | title = Sesquiterpene synthases from grand fir (Abies grandis). Comparison of constitutive and wound-induced activities, and cDNA isolation, characterization, and bacterial expression of δ-selinene synthase and γ-humulene synthase | journal = The Journal of Biological Chemistry | volume = 273 | issue = 4 | pages = 2078–89 | date = January 1998 | pmid = 9442047 | doi = 10.1074/jbc.273.4.2078 | doi-access = free }}{{cite journal | vauthors = Little DB, Croteau RB | title = Alteration of product formation by directed mutagenesis and truncation of the multiple-product sesquiterpene synthases δ-selinene synthase and γ-humulene synthase | journal = Archives of Biochemistry and Biophysics | volume = 402 | issue = 1 | pages = 120–35 | date = June 2002 | pmid = 12051690 | doi = 10.1016/S0003-9861(02)00068-1 }} This enzyme catalyses the following chemical reaction

: (2E,6E)-farnesyl diphosphate \rightleftharpoons (+)-δ-selinene + diphosphate

Initial cyclization gives germacrene C in an enzyme bound form.

References

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