:(+)-epi-alpha-bisabolol synthase

{{Short description|Class of enzymes}}

{{Infobox enzyme

| Name = (+)-epi-α-bisabolol synthase

| EC_number = 4.2.3.138

| CAS_number =

| GO_code =

| image =

| width =

| caption =

}}

(+)-epi-α-Bisabolol synthase (EC 4.2.3.138) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-epi-α-bisabolol-forming).{{cite journal | vauthors = Attia M, Kim SU, Ro DK | title = Molecular cloning and characterization of (+)-epi-α-bisabolol synthase, catalyzing the first step in the biosynthesis of the natural sweetener, hernandulcin, in Lippia dulcis | journal = Archives of Biochemistry and Biophysics | volume = 527 | issue = 1 | pages = 37–44 | date = November 2012 | pmid = 22867794 | doi = 10.1016/j.abb.2012.07.010 }} This enzyme catalyses the following chemical reaction:

: (2E,6E)-farnesyl diphosphate + H₂O $\backslash rightleftharpoons$ (+)-epi-α-bisabolol + diphosphate

This enzyme is isolated from the plant Phyla dulcis (Aztec sweet herb).