:(+)-germacrene D synthase

{{Short description|Class of enzymes}}

{{Infobox enzyme

| Name = (+)-germacrene D synthase

| EC_number = 4.2.3.77

| CAS_number =

| GO_code =

| image =

| width =

| caption =

}}

(+)-Germacrene D synthase (EC 4.2.3.77) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((+)-germacrene-D-forming).{{cite journal | vauthors = Picaud S, Olsson ME, Brodelius M, Brodelius PE | title = Cloning, expression, purification and characterization of recombinant (+)-germacrene D synthase from Zingiber officinale | journal = Archives of Biochemistry and Biophysics | volume = 452 | issue = 1 | pages = 17–28 | date = August 2006 | pmid = 16839518 | doi = 10.1016/j.abb.2006.06.007 }} This enzyme catalyses the following chemical reaction

: (2E,6E)-farnesyl diphosphate $\backslash rightleftharpoons$ (+)-germacrene D + diphosphate

This enzyme requires Mg²⁺, Mn²⁺, Ni²⁺ or Co²⁺.