:1,1,2-Trichloroethane

{{chembox

| Watchedfields = changed

| verifiedrevid = 477201733

| Name = 1,1,2-Trichloroethane

| ImageFileL1_Ref = {{chemboximage|correct|??}}

| ImageFileL1 = 1,1,2-Trichloroethane.svg

| ImageNameL1 = 1,1,2-Trichloroethane

| ImageFileR1 = 1,1,2-trichloroethane-3D-vdW.png

| PIN = 1,1,2-Trichloroethane

| OtherNames = 1,1,2-TCA
vinyl trichloride

symmetrical Trichloroethane
monochlorethylen chloride (archaic)

| Section1 = {{Chembox Identifiers

| PubChem = 6574

| InChI = 1/C2H3Cl3/c3-1-2(4)5/h2H,1H2

| InChIKey = UBOXGVDOUJQMTN-UHFFFAOYAA

| SMILES1 = C(C(Cl)Cl)Cl

| ChEMBL_Ref = {{ebicite|correct|EBI}}

| ChEMBL = 43882

| StdInChI_Ref = {{stdinchicite|correct|chemspider}}

| StdInChI = 1S/C2H3Cl3/c3-1-2(4)5/h2H,1H2

| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}

| StdInChIKey = UBOXGVDOUJQMTN-UHFFFAOYSA-N

| CASNo = 79-00-5

| CASNo_Ref = {{cascite|correct|CAS}}

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = 28E9ERN9WU

| SMILES = ClCC(Cl)Cl

| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}

| ChEBI_Ref = {{ebicite|correct|EBI}}

| ChEBI = 36018

| ChemSpiderID =6326

| KEGG_Ref = {{keggcite|correct|kegg}}

| KEGG = C19536

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| Section2 = {{Chembox Properties

| Formula = C{{sub|2}}H{{sub|3}}Cl{{sub|3}}

| MolarMass = 133.40 g/mol

| Density = 1.435 g/cm{{sup|3}}

| MeltingPtC = -37

| MeltingPt_notes =

| BoilingPtC = 110 to 115

| BoilingPt_notes =

| Appearance = colorless liquid

| Odor = sweet, chloroform-like (in high concentrations)

| Solubility = 0.4% (20°C)

| VaporPressure = 19 mmHg (20°C)

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| Section7 = {{Chembox Hazards

| MainHazards=

| NFPA-H = 3

| NFPA-F = 1

| NFPA-R =

| PEL = TWA 10 ppm (45 mg/m{{sup|3}}) [skin]{{PGCH|0628}}

| ExploLimits = 6–15.5%

| IDLH = Ca [100 ppm]

| REL = Ca TWA 10 ppm (45 mg/m{{sup|3}}) [skin]

| LD50 = 1200 mg/kg (rat, orally)1,1,2-Trichloroethane toxicity

| LCLo = 13,100 mg/m{{sup|3}} (cat, 4.5 hr)
2000 ppm (rat, 4 hr){{IDLH|79005|1,1,2-Trichloroethane}}

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| Section8 = {{Chembox Related

| OtherCompounds = 1,1,1-Trichloroethane; Trichloroethylene}}

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1,1,2-Trichloroethane, vinyl trichloride or 1,1,2-TCA, is an organochloride solvent with the molecular formula {{chem2|C2H3Cl3}} and the structural formula {{chem2|CH2Cl\sCHCl2}}. It is a colourless, sweet-smelling liquid that does not dissolve in water, but is soluble in most organic solvents. It is an isomer of 1,1,1-trichloroethane, and a byproduct of its manufacture.

It is used as a solvent and as an intermediate in the synthesis of 1,1-dichloroethylene.{{cite report |title=Toxicological profile for 1,1,2-trichloroethane |publisher=Agency for Toxic Substances and Disease Registry (ATSDR) |date=March 2021 |url=https://www.atsdr.cdc.gov/toxprofiles/tp148.pdf |access-date=2023-08-23 |archive-date=2022-03-05 |archive-url=https://web.archive.org/web/20220305233413/https://www.atsdr.cdc.gov/toxprofiles/tp148.pdf |url-status=live}}

==Toxicity==

1,1,2-Trichloroethane may be harmful by inhalation, ingestion, and skin contact. It is a respiratory and eye irritant. 1,1,2-TCA is a central nervous system depressant and inhalation of vapors may cause dizziness, drowsiness, headache, nausea, shortness of breath, and unconsciousness.{{cite web | title = Safety (MSDS) data for 1,1,2-trichloroethane |url = https://www.spectrumchemical.com/MSDS/TCI-T0381.pdf}}

The Occupational Safety and Health Administration and National Institute for Occupational Safety and Health have set occupational exposure limits to 1,1,2-trichloroethane at 10 ppm over an eight-hour time-weighted average.[https://www.cdc.gov/niosh/npg/npgd0628.html CDC - NIOSH Pocket Guide to Chemical Hazards]

References