:1,1,2-Trichloroethane
{{chembox
| Watchedfields = changed
| verifiedrevid = 477201733
| Name = 1,1,2-Trichloroethane
| ImageFileL1_Ref = {{chemboximage|correct|??}}
| ImageFileL1 = 1,1,2-Trichloroethane.svg
| ImageNameL1 = 1,1,2-Trichloroethane
| ImageFileR1 = 1,1,2-trichloroethane-3D-vdW.png
| PIN = 1,1,2-Trichloroethane
| OtherNames = 1,1,2-TCA
vinyl trichloride
symmetrical Trichloroethane
monochlorethylen chloride (archaic)
| Section1 = {{Chembox Identifiers
| PubChem = 6574
| InChI = 1/C2H3Cl3/c3-1-2(4)5/h2H,1H2
| InChIKey = UBOXGVDOUJQMTN-UHFFFAOYAA
| SMILES1 = C(C(Cl)Cl)Cl
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 43882
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C2H3Cl3/c3-1-2(4)5/h2H,1H2
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = UBOXGVDOUJQMTN-UHFFFAOYSA-N
| CASNo = 79-00-5
| CASNo_Ref = {{cascite|correct|CAS}}
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 28E9ERN9WU
| SMILES = ClCC(Cl)Cl
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 36018
| ChemSpiderID =6326
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = C19536
}}
| Section2 = {{Chembox Properties
| Formula = C{{sub|2}}H{{sub|3}}Cl{{sub|3}}
| MolarMass = 133.40 g/mol
| Density = 1.435 g/cm{{sup|3}}
| MeltingPtC = -37
| MeltingPt_notes =
| BoilingPtC = 110 to 115
| BoilingPt_notes =
| Appearance = colorless liquid
| Odor = sweet, chloroform-like (in high concentrations)
| VaporPressure = 19 mmHg (20°C)
}}
| Section7 = {{Chembox Hazards
| MainHazards=
| NFPA-H = 3
| NFPA-F = 1
| NFPA-R =
| PEL = TWA 10 ppm (45 mg/m{{sup|3}}) [skin]{{PGCH|0628}}
| REL = Ca TWA 10 ppm (45 mg/m{{sup|3}}) [skin]
| LD50 = 1200 mg/kg (rat, orally)1,1,2-Trichloroethane toxicity
| LCLo = 13,100 mg/m{{sup|3}} (cat, 4.5 hr)
2000 ppm (rat, 4 hr){{IDLH|79005|1,1,2-Trichloroethane}}
}}
| Section8 = {{Chembox Related
| OtherCompounds = 1,1,1-Trichloroethane; Trichloroethylene}}
}}
1,1,2-Trichloroethane, vinyl trichloride or 1,1,2-TCA, is an organochloride solvent with the molecular formula {{chem2|C2H3Cl3}} and the structural formula {{chem2|CH2Cl\sCHCl2}}. It is a colourless, sweet-smelling liquid that does not dissolve in water, but is soluble in most organic solvents. It is an isomer of 1,1,1-trichloroethane, and a byproduct of its manufacture.
It is used as a solvent and as an intermediate in the synthesis of 1,1-dichloroethylene.{{cite report |title=Toxicological profile for 1,1,2-trichloroethane |publisher=Agency for Toxic Substances and Disease Registry (ATSDR) |date=March 2021 |url=https://www.atsdr.cdc.gov/toxprofiles/tp148.pdf |access-date=2023-08-23 |archive-date=2022-03-05 |archive-url=https://web.archive.org/web/20220305233413/https://www.atsdr.cdc.gov/toxprofiles/tp148.pdf |url-status=live}}
==Toxicity==
1,1,2-Trichloroethane may be harmful by inhalation, ingestion, and skin contact. It is a respiratory and eye irritant. 1,1,2-TCA is a central nervous system depressant and inhalation of vapors may cause dizziness, drowsiness, headache, nausea, shortness of breath, and unconsciousness.{{cite web | title = Safety (MSDS) data for 1,1,2-trichloroethane |url = https://www.spectrumchemical.com/MSDS/TCI-T0381.pdf}}
The Occupational Safety and Health Administration and National Institute for Occupational Safety and Health have set occupational exposure limits to 1,1,2-trichloroethane at 10 ppm over an eight-hour time-weighted average.[https://www.cdc.gov/niosh/npg/npgd0628.html CDC - NIOSH Pocket Guide to Chemical Hazards]
References
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