:21S rRNA pseudouridine2819 synthase

{{Short description|Class of enzymes}}

{{Infobox enzyme

| Name = 21S rRNA pseudouridine²⁸¹⁹ synthase

| EC_number = 5.4.99.43

| CAS_number =

| GO_code =

| image =

| width =

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21S rRNA pseudouridine²⁸¹⁹ synthase ({{EnzExplorer|5.4.99.43}}, Pus5p) is an enzyme with systematic name 21S rRNA-uridine²⁸¹⁹ uracil mutase.{{cite journal | vauthors = Ansmant I, Massenet S, Grosjean H, Motorin Y, Branlant C | title = Identification of the Saccharomyces cerevisiae RNA:pseudouridine synthase responsible for formation of psi(2819) in 21S mitochondrial ribosomal RNA | journal = Nucleic Acids Research | volume = 28 | issue = 9 | pages = 1941–6 | date = May 2000 | pmid = 10756195 | pmc = 103309 | doi = 10.1093/nar/28.9.1941 }} This enzyme catalyses the following chemical reaction

: 21S rRNA uridine²⁸¹⁹ $\backslash rightleftharpoons$ 21S rRNA pseudouridine²⁸¹⁹

The enzyme specifically acts on uridine²⁸¹⁹ in 21S rRNA.