:3-Nitrobenzanthrone
{{chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 477219884
| ImageFile = 3-Nitrobenzanthrone.png
| ImageSize=
| PIN = 3-Nitro-7H-benzo[de]anthracen-7-one
| OtherNames =
|Section1={{Chembox Identifiers
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 2103821
| InChI = 1/C17H9NO3/c19-17-12-5-2-1-4-10(12)11-8-9-15(18(20)21)13-6-3-7-14(17)16(11)13/h1-9H
| InChIKey = QAJOWHGESRCVLY-UHFFFAOYAK
| SMILES1 = [O-][N+](=O)c2c1cccc4c1c(cc2)c3c(cccc3)C4=O
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C17H9NO3/c19-17-12-5-2-1-4-10(12)11-8-9-15(18(20)21)13-6-3-7-14(17)16(11)13/h1-9H
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = QAJOWHGESRCVLY-UHFFFAOYSA-N
| CASNo_Ref = {{cascite|changed|??}}
| CASNo = 17117-34-9
| PubChem = 2825690
| KEGG = C20824
| UNII = O4OJW7BC7W
| SMILES = O=C2C1=CC=CC=C1C4=C3C2=CC=CC3C([N+]([O-])=O)C=C4
}}
|Section2={{Chembox Properties
| Formula = C17H9NO3
| MolarMass = 275.26 g/mol
| Appearance =
| Density =
| MeltingPtC = 248
| MeltingPt_ref = {{cite journal |title=The environmental carcinogen 3-nitrobenzanthrone and its main metabolite 3-aminobenzanthrone enhance formation of reactive oxygen intermediates in human A549 lung epithelial cells |author =Hansen, Tanja |author2 =Seidel, Albrecht |author3 =Borlak, Juergen |journal=Toxicology and Applied Pharmacology |year=2007 |volume=221 |issue=2 |pages=222–234 |doi=10.1016/j.taap.2007.03.003 |pmid=17477947|s2cid =25295474 |url =http://publica.fraunhofer.de/documents/N-60792.html |url-access=subscription }}
| BoilingPt =
| Solubility = }}
|Section3={{Chembox Hazards
| MainHazards = extremely carcinogenic
| FlashPt =
| AutoignitionPt = }}
}}
3-Nitrobenzanthrone (3-nitro-7H-benz[de]anthracen-7-one) is a chemical compound emitted in diesel exhaust; it is a potent carcinogen.{{cite journal
| journal = Mutagenesis
| year = 2005
| volume = 20
| issue = 6
| pages = 399–410
| doi = 10.1093/mutage/gei057
| title = 3-Nitrobenzanthrone, a potential human cancer hazard in diesel exhaust and urban air pollution: a review of the evidence
| author = Volker M. Arlt
| pmid = 16199526| doi-access = free| citeseerx = 10.1.1.1001.7655}} It produced the highest score ever reported in the Ames test, a standard measure of the cancer-causing potential of toxic chemicals, far greater than the previous known strongest (1,8-dinitropyrene, which is also found in diesel exhaust).{{cite journal | journal = New Scientist | date = Oct 25, 1997 | pages = 4 |author = Fred Pearce | url=https://www.newscientist.com/article/mg15621050.200-devil-in-the-diesel--lorries-belch-out-what-may-be-the-most.html | title = Devil in the diesel}}
See also
References
{{Reflist}}
{{DEFAULTSORT:Nitrobenzanthrone, 3-}}
Category:Polycyclic aromatic compounds
Category:IARC Group 2B carcinogens
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