:7,8-Dihydroneopterin triphosphate
{{Chembox
| Verifiedfields = changed
| verifiedrevid = 477226319
| ImageFile = 7,8-Dihydroneopterin triphosphate.png
| ImageSize = 200px
| PIN = (2R,3S)-3-(2-Amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)-2,3-dihydroxypropyl tetrahydrogen triphosphate
| OtherNames = DHNTP
|Section1={{Chembox Identifiers
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 108735
| InChI = 1/C9H16N5O13P3/c10-9-13-7-5(8(17)14-9)12-3(1-11-7)6(16)4(15)2-25-29(21,22)27-30(23,24)26-28(18,19)20/h4,6,15-16H,1-2H2,(H,21,22)(H,23,24)(H2,18,19,20)(H4,10,11,13,14,17)/t4-,6+/m1/s1
| InChIKey = DGGUVLXVLHAAGT-XINAWCOVBB
| SMILES1 = O=P(O)(O)OP(=O)(O)OP(=O)(O)OC[C@@H](O)[C@@H](O)C/1=N/C=2C(=O)\N=C(/NC=2NC\1)N
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C9H16N5O13P3/c10-9-13-7-5(8(17)14-9)12-3(1-11-7)6(16)4(15)2-25-29(21,22)27-30(23,24)26-28(18,19)20/h4,6,15-16H,1-2H2,(H,21,22)(H,23,24)(H2,18,19,20)(H4,10,11,13,14,17)/t4-,6+/m1/s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = DGGUVLXVLHAAGT-XINAWCOVSA-N
| CASNo_Ref = {{cascite|changed|??}}
| CASNo = 17088-65-2
| PubChem = 121885
| ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 18372
| KEGG = C04895
| SMILES = O=C1C2=C(NCC([C@@H]([C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O)O)=N2)NC(N)=N1}}
|Section2={{Chembox Properties
| C=9 | H=16 | N=5 | O=13 | P=3
| Appearance =
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|Section3={{Chembox Hazards
| MainHazards =
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7,8-Dihydroneopterin triphosphate (DHNTP) is an intermediate in tetrahydrobiopterin biosynthesis. It is transformed by 6-pyruvoyltetrahydropterin synthase into 6-pyruvoyl-tetrahydropterin.{{cite web|url=http://ghr.nlm.nih.gov/gene/PTS|title=PTS gene|author=Genetics Home Reference|website=Genetics Home Reference|access-date=3 May 2018}} It is also used in the Queuosine/Archeosine Pathway.{{citation needed|date=May 2023}}
Synonyms
- Dihydroneopterin Triphosphate{{cite web|url=http://www.chemdrug.com/databases/10_1_pbosvwvgpobtpfdn.html|title=dihydroneopterin triphosphate ,CHEBI:18372,7,8-dihydroneopterin 3'-化学物质数据库|website=www.chemdrug.com|access-date=3 May 2018}}
- 7,8-dihydroneopterin 3'-triphosphate
- 6-(L-erythro-1,2-Dihydroxypropyl 3-triphosphate)-7,8-dihydropterin
- 6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydropterin
- 6-(L-erythro-1,2-dihydroxy-3-triphosphooxypropyl)-7,8-dihydropterin
- 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate
- 2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridinetriphosphate
- (2R,3S)-3-(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)-2,3-dihydroxypropyl tetrahydrogen triphosphate
References
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