:Abietadiene hydroxylase

{{Short description|Class of enzymes}}

{{Infobox enzyme

| Name = Abieta-7,13-diene hydroxylase

| EC_number = 1.14.13.108

| CAS_number =

| GO_code =

| image =

| width =

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Abieta-7,13-diene hydroxylase ({{EC number|1.14.13.108}}) is an enzyme with systematic name abieta-7,13-diene,NADPH:oxygen oxidoreductase (18-hydroxylating).{{cite journal | vauthors = Funk C, Croteau R | title = Diterpenoid resin acid biosynthesis in conifers: characterization of two cytochrome P450-dependent monooxygenases and an aldehyde dehydrogenase involved in abietic acid biosynthesis | journal = Archives of Biochemistry and Biophysics | volume = 308 | issue = 1 | pages = 258–66 | date = January 1994 | pmid = 8311462 | doi = 10.1006/abbi.1994.1036 }}{{cite journal | vauthors = Funk C, Lewinsohn E, Vogel BS, Steele CL, Croteau R | title = Regulation of Oleoresinosis in Grand Fir (Abies grandis) (Coordinate Induction of Monoterpene and Diterpene Cyclases and Two Cytochrome P450-Dependent Diterpenoid Hydroxylases by Stem Wounding) | journal = Plant Physiology | volume = 106 | issue = 3 | pages = 999–1005 | date = November 1994 | pmid = 12232380 | pmc = 159624 | doi = 10.1104/pp.106.3.999 }} This enzyme catalyses the following chemical reaction

: abieta-7,13-diene + NADPH + H+ + O2 \rightleftharpoons abieta-7,13-dien-18-ol + NADP+ + H2O

Abietadiene hydroxylase is a heme-thiolate protein (P-450).

References

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