:Acetoxycycloheximide

{{Chembox

| ImageFile = Acetoxycycloheximide.svg

| ImageSize = 175

| IUPACName = (1R,3S,5S)-3-[(1R)-2-(2,6-Dioxo-4-piperidinyl)-1-hydroxyethyl]-1,5-dimethyl-4-oxocyclohexyl acetate

| OtherNames = Acetyloxycycloheximide
E-73

| Section1 = {{Chembox Identifiers

| CASNo = 2885-39-4

| CASNo_Ref = {{cascite|correct|CAS}}

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = UX3Y1I395S

| PubChem = 73396

| ChemSpiderID = 66113

| SMILES = C[C@H]1C[C@@](C[C@H](C1=O)[C@@H](CC2CC(=O)NC(=O)C2)O)(C)OC(=O)C

| StdInChI = 1S/C17H25NO6/c1-9-7-17(3,24-10(2)19)8-12(16(9)23)13(20)4-11-5-14(21)18-15(22)6-11/h9,11-13,20H,4-8H2,1-3H3,(H,18,21,22)/t9-,12-,13+,17+/m0/s1

| StdInChIKey = UFDHNJJHPSGMFX-SQUSCZTCSA-N

}}

| Section2 = {{Chembox Properties

| C=17 | H=25 | N=1 | O=6

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|Section3={{Chembox Hazards

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Acetoxycycloheximide is an organic chemical compound. It can be considered as the acetylated analogue of cycloheximide. It is a potent protein synthesis inhibitor in animal cells{{cite book|last=Mahy|first=Brian W J|title=A dictionary of virology|url=https://archive.org/details/dictionaryofviro0000mahy|url-access=registration|date=2001|publisher=Academic Press|location=San Diego, Calif. [u.a.]|isbn=0-12-465327-8|pages=[https://archive.org/details/dictionaryofviro0000mahy/page/2 2]|edition=3.}} and can inhibit the formation of memories.{{cite journal|last1=Flood|first1=James F.|last2=Bennett|first2=Edward L.|last3=Orme|first3=Ann E.|last4=Rosenzweig|first4=Mark R.|title=Effects of protein synthesis inhibition on memory for active avoidance training|journal=Physiology & Behavior|date=February 1975|volume=14|issue=2|pages=177–184|doi=10.1016/0031-9384(75)90163-8|pmid=1161822|s2cid=31577844|url=https://escholarship.org/content/qt02h826wv/qt02h826wv.pdf?t=p0lnws}}{{cite journal|last1=Flexner|first1=L. B.|last2=Flexner|first2=J. B.|last3=Roberts|first3=R. B.|title=Stages of memory in mice treated with acetoxycycloheximide before or immediately after learning.|journal=Proceedings of the National Academy of Sciences|date=1 August 1966|volume=56|issue=2|pages=730–735|doi=10.1073/pnas.56.2.730|pmc=224433|pmid=5229991|bibcode=1966PNAS...56..730F |doi-access=free}}

See also

References