:Adamalysin

{{Short description|Class of enzymes}}

{{Infobox enzyme

| Name = Adamalysin

| EC_number = 3.4.24.46

| CAS_number = 74812-51-4

| GO_code =

| image =

| width =

| caption =

}}

Adamalysin ({{EC number|3.4.24.46}}, Crotalus adamanteus metalloendopeptidase, proteinase I and II, Crotalus adamanteus venom proteinase II, adamalysin II) is an enzyme.{{cite journal | vauthors = Kurecki T, Laskowski M, Kress LF | title = Purification and some properties of two proteinases from Crotalus adamanteus venom that inactivate human alpha 1-proteinase inhibitor | journal = The Journal of Biological Chemistry | volume = 253 | issue = 22 | pages = 8340–5 | date = November 1978 | pmid = 309470 }} This enzyme catalyses the following chemical reaction

: Cleavage of Phe¹-Val, His⁵-Leu, His¹⁰-Leu, Ala¹⁴-Leu, Leu¹⁵-Tyr, and Tyr¹⁶-Leu of insulin B chain

This enzyme is present in the venom of the eastern diamondback rattlesnake (Crotalus adamanteus).