:Aminopeptidase Y

{{Short description|Class of enzymes}}

{{Infobox enzyme

| Name = Aminopeptidase Y

| EC_number = 3.4.11.15

| CAS_number = 114796-97-3

| GO_code =

| image = 4x8i.jpg

| width = 270

| caption = Lysyl aminopeptidase dodekamer, Pyrococcus furiosus

}}

Aminopeptidase Y ({{EC number|3.4.11.15}}, aminopeptidase Co, aminopeptidase (cobalt-activated), lysyl aminopeptidase) is an enzyme.{{cite journal | vauthors = Achstetter T, Ehmann C, Wolf DH | title = Aminopeptidase Co, a new yeast peptidase | journal = Biochemical and Biophysical Research Communications | volume = 109 | issue = 2 | pages = 341–7 | date = November 1982 | pmid = 6758786 | doi = 10.1016/0006-291x(82)91726-0 }}{{cite journal | vauthors = Yasuhara T, Nakai T, Ohashi A | title = Aminopeptidase Y, a new aminopeptidase from Saccharomyces cerevisiae. Purification, properties, localization, and processing by protease B | journal = The Journal of Biological Chemistry | volume = 269 | issue = 18 | pages = 13644–50 | date = May 1994 | doi = 10.1016/S0021-9258(17)36878-3 | pmid = 8175799 | doi-access = free }}{{cite journal | vauthors = Nishizawa M, Yasuhara T, Nakai T, Fujiki Y, Ohashi A | title = Molecular cloning of the aminopeptidase Y gene of Saccharomyces cerevisiae. Sequence analysis and gene disruption of a new aminopeptidase | journal = The Journal of Biological Chemistry | volume = 269 | issue = 18 | pages = 13651–5 | date = May 1994 | doi = 10.1016/S0021-9258(17)36879-5 | pmid = 8175800 | doi-access = free }} This enzyme catalyses the following chemical reaction

: Preferentially, release of N-terminal lysine

This enzyme requires Co²⁺. It is inhibited by Zn²⁺ and Mn²⁺.