:Beta-amyrin 11-oxidase

{{Short description|Class of enzymes}}

{{Infobox enzyme

| Name = Beta-amyrin 11-oxidase

| EC_number = 1.14.13.134

| CAS_number =

| GO_code =

| image =

| width =

| caption =

}}

Beta-amyrin 11-oxidase ({{EC number|1.14.13.134}}, CYP88D6) is an enzyme with systematic name beta-amyrin,NADPH:oxygen oxidoreductase (hydroxylating).{{cite journal | vauthors = Seki H, Ohyama K, Sawai S, Mizutani M, Ohnishi T, Sudo H, Akashi T, Aoki T, Saito K, Muranaka T | title = Licorice beta-amyrin 11-oxidase, a cytochrome P450 with a key role in the biosynthesis of the triterpene sweetener glycyrrhizin | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 105 | issue = 37 | pages = 14204–9 | date = September 2008 | pmid = 18779566 | pmc = 2532699 | doi = 10.1073/pnas.0803876105 | bibcode = 2008PNAS..10514204S | doi-access = free }} This enzyme catalyses the following chemical reaction

: beta-amyrin + 2 O₂ + 2 NADPH + 2 H⁺ $\backslash rightleftharpoons$ 11-oxo-beta-amyrin + 3 H₂O + 2 NADP⁺ (overall reaction)

:(1a) beta-amyrin + O₂ + NADPH + H⁺ $\backslash rightleftharpoons$ 11alpha-hydroxy-beta-amyrin + H₂O + NADP⁺

:(1b) 11alpha-hydroxy-beta-amyrin + O₂ + NADPH + H⁺ $\backslash rightleftharpoons$ 11-oxo-beta-amyrin + 2 H₂O + NADP⁺

Beta-amyrin 11-oxidase requires cytochrome P450.