:Beta-santalene synthase

{{Infobox enzyme

| Name = β-santalene synthase

| EC_number = 4.2.3.83

| CAS_number =

| GO_code =

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β-Santalene synthase (EC 4.2.3.83) is an enzyme with systematic name (2E,6E)-farnesyl diphosphate lyase (cyclizing, (–)-β-santalene-forming).{{cite journal | vauthors = Jones CG, Moniodis J, Zulak KG, Scaffidi A, Plummer JA, Ghisalberti EL, Barbour EL, Bohlmann J | title = Sandalwood fragrance biosynthesis involves sesquiterpene synthases of both the terpene synthase (TPS)-a and TPS-b subfamilies, including santalene synthases | journal = The Journal of Biological Chemistry | volume = 286 | issue = 20 | pages = 17445–54 | date = May 2011 | pmid = 21454632 | pmc = 3093818 | doi = 10.1074/jbc.m111.231787 | doi-access = free }} This enzyme catalyses the following chemical reaction

: (2E,6E)-farnesyl diphosphate $\backslash rightleftharpoons$ (–)-β-santalene + diphosphate

The enzyme synthesizes a mixture of sesquiterpenoids from (2E,6E)-farnesyl diphosphate.