:CDw17 antigen

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CDw17 antigen is a lactosylceramide,{{MeshName|CDw17+antigen}} a class of glycosphingolipids found in microdomains on the plasma layers of numerous cells. It is found on human neutrophils, basophils, monocyte, platelets, tonsillar CD45+ dendritic cells, epithelial cells, endothelial cells in intestinal epithelium, and on post-proliferative granulocytes in the bone marrow. {{Cite book | vauthors = Barclay AN, Brown MH, Law SK, McKnight AJ, Tomlinson MG, van der Merwe PA | chapter = CDw17 | page = 176 | veditors = Barclay AN |title=The Leucocyte Antigen Factsbook |date=1997 |publisher=Academic Press |isbn=978-0-12-078185-0 |doi=10.1016/B978-012078185-0/50452-2 |edition=2nd |series=Factsbook Series |location=San Diego}}

CDw17 acts as a precursor for biosynthesis of glycosphingolipids.{{cite journal | vauthors = Chatterjee S, Balram A, Li W | title = Convergence: Lactosylceramide-Centric Signaling Pathways Induce Inflammation, Oxidative Stress, and Other Phenotypic Outcomes | journal = International Journal of Molecular Sciences | volume = 22 | issue = 4 | pages = 1816 | date = February 2021 | pmid = 33673027 | pmc = 7917694 | doi = 10.3390/ijms22041816 | doi-access = free }}

The enzyme A4GALT acts upon it, aiding transfer of galactose to lactosylceramide to form globotriaosylceramide.