:Carlactone synthase

{{Infobox enzyme

| Name = Carlactone synthase

| EC_number = 1.13.11.69

| CAS_number =

| GO_code =

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Carlactone synthase ({{EC number|1.13.11.69}}, CCD8 (gene), MAX4 (gene), NCED8 (gene)) is an enzyme with systematic name 9-cis-10'-apo-beta-carotenal:O2 oxidoreductase (14,15-cleaving, carlactone-forming).{{cite journal | vauthors = Sorefan K, Booker J, Haurogné K, Goussot M, Bainbridge K, Foo E, Chatfield S, Ward S, Beveridge C, Rameau C, Leyser O | title = MAX4 and RMS1 are orthologous dioxygenase-like genes that regulate shoot branching in Arabidopsis and pea | journal = Genes & Development | volume = 17 | issue = 12 | pages = 1469–74 | date = June 2003 | pmid = 12815068 | pmc = 196077 | doi = 10.1101/gad.256603 }}{{cite journal | vauthors = Schwartz SH, Qin X, Loewen MC | title = The biochemical characterization of two carotenoid cleavage enzymes from Arabidopsis indicates that a carotenoid-derived compound inhibits lateral branching | journal = The Journal of Biological Chemistry | volume = 279 | issue = 45 | pages = 46940–5 | date = November 2004 | pmid = 15342640 | doi = 10.1074/jbc.M409004200 | doi-access = free }}{{cite journal | vauthors = Alder A, Jamil M, Marzorati M, Bruno M, Vermathen M, Bigler P, Ghisla S, Bouwmeester H, Beyer P, Al-Babili S | title = The path from β-carotene to carlactone, a strigolactone-like plant hormone | journal = Science | volume = 335 | issue = 6074 | pages = 1348–51 | date = March 2012 | pmid = 22422982 | doi = 10.1126/science.1218094 | s2cid = 29137583 | url = http://nbn-resolving.de/urn:nbn:de:bsz:352-235683 }} This enzyme catalyses the following chemical reaction

: 9-cis-10'-apo-beta-carotenal + 2 O2 \rightleftharpoons carlactone + (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal

Carlactone synthase contains Fe2+.

References

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