:Chamazulene
{{disputed|date=August 2021}}
{{Chembox
| ImageFile = Chamazulene.svg
| ImageSize =
| PIN = 7-Ethyl-1,4-dimethylazulene
| OtherNames = 1,4-Dimethyl-7-ethylazulene; Ba 2784; Camazulene; Chamazulen; Dimethulen; Dimethulene
|Section1={{Chembox Identifiers
| CASNo = 529-05-5
| CASNo_Ref = {{cascite|correct|}}
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = Z439UH6E5F
| PubChem = 10719
| ChemSpiderID = 10268
| SMILES = c1(ccc(c2ccc(c2c1)C)C)CC
| InChI = 1/C14H16/c1-4-12-7-5-10(2)13-8-6-11(3)14(13)9-12/h5-9H,4H2,1-3H3
| InChIKey = GXGJIOMUZAGVEH-UHFFFAOYAM
| StdInChI = 1S/C14H16/c1-4-12-7-5-10(2)13-8-6-11(3)14(13)9-12/h5-9H,4H2,1-3H3
| StdInChIKey = GXGJIOMUZAGVEH-UHFFFAOYSA-N
}}
|Section2={{Chembox Properties
| C=14 | H=16
| Appearance = Blue oilThe Merck Index, 11th Edition, 2031
| MeltingPt =
| BoilingPtC = 161
| BoilingPt_notes = (at 12 mmHg)
| Solubility =
}}
|Section3={{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt =
| LD50 = 3 g/kg (i.m., mouse)
}}
}}
Chamazulene is an aromatic chemical compound with the molecular formula C14H16 found in a variety of plants including in chamomile (Matricaria chamomilla), wormwood (Artemisia absinthium), and yarrow (Achillea millefolium). It is a blue-violet derivative of azulene which is biosynthesized from the sesquiterpene matricin.{{cite journal | pmid = 7997466 | year = 1994 | last1 = Safayhi | first1 = H | last2 = Sabieraj | first2 = J | last3 = Sailer | first3 = ER | last4 = Ammon | first4 = HP | title = Chamazulene: An antioxidant-type inhibitor of leukotriene B4 formation | volume = 60 | issue = 5 | pages = 410–3 | doi = 10.1055/s-2006-959520 | journal = Planta Medica}}
:File:Chamazulen synthesis.png of chamazulene (3) from matricin (1) via a carboxylic acid of chamazulene (2).]]{{clear-left}}
Chamazulene has anti-inflammatory properties in vivo and inhibits the CYP1A2 enzyme.