:Colneleate synthase

{{Short description|Enzyme}}

{{Infobox enzyme

| Name = Colneleate synthase

| EC_number = 4.2.1.121

| CAS_number =

| GO_code =

| image =

| width =

| caption =

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Colneleate synthase ({{EnzExplorer|4.2.1.121}}, 9-divinyl ether synthase, 9-DES, CYP74D, CYP74D1, CYP74 cytochrome P-450, DES1) is an enzyme with systematic name (8E)-9-((1E,3E)-nona-1,3-dien-1-yloxy)non-8-enoate synthase.{{cite journal | vauthors = Stumpe M, Kandzia R, Göbel C, Rosahl S, Feussner I | title = A pathogen-inducible divinyl ether synthase (CYP74D) from elicitor-treated potato suspension cells | journal = FEBS Letters | volume = 507 | issue = 3 | pages = 371–6 | date = November 2001 | pmid = 11696374 | doi = 10.1016/s0014-5793(01)03019-8 | doi-access = free }}{{cite journal | vauthors = Itoh A, Howe GA | title = Molecular cloning of a divinyl ether synthase. Identification as a CYP74 cytochrome P-450 | journal = The Journal of Biological Chemistry | volume = 276 | issue = 5 | pages = 3620–7 | date = February 2001 | pmid = 11060314 | doi = 10.1074/jbc.m008964200 | doi-access = free }}{{cite journal | vauthors = Fammartino A, Cardinale F, Göbel C, Mène-Saffrané L, Fournier J, Feussner I, Esquerré-Tugayé MT | title = Characterization of a divinyl ether biosynthetic pathway specifically associated with pathogenesis in tobacco | journal = Plant Physiology | volume = 143 | issue = 1 | pages = 378–88 | date = January 2007 | pmid = 17085514 | pmc = 1761965 | doi = 10.1104/pp.106.087304 }}{{cite journal | vauthors = Hamberg M | title = Hidden stereospecificity in the biosynthesis of divinyl ether fatty acids | journal = The FEBS Journal | volume = 272 | issue = 3 | pages = 736–43 | date = February 2005 | pmid = 15670154 | doi = 10.1111/j.1742-4658.2004.04510.x | doi-access = free }} This enzyme catalyses the following chemical reaction

: (9S,10E,12Z)-9-hydroperoxyoctadeca-10,12-dienoate $\backslash rightleftharpoons$

:: (8E)-9-[(1E,3Z)-nona-1,3-dien-1-yloxy]non-8-enoate + H₂O

This enzyme is a heme-thiolate protein (P450).