:Corynoline

{{Chembox

| ImageFile = Corynoline.svg

| ImageSize = 150px

| ImageAlt =

| IUPACName = 13-Methylchelidonine

| SystematicName = (5bR,6S,12bR)-5b,13-Dimethyl-5b,6,7,12b,13,14-hexahydro-2H,10H-[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-h]phenanthridin-6-ol

| OtherNames =

|Section1={{Chembox Identifiers

| CASNo = 18797-79-0

| CASNo_Ref = {{Cascite|changed|CAS}}

| CASNo1 = 68035-45-0

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = ZQ9W3JU6N3

| ChEBI = 65660

| ChEMBL = 4126384

| EINECS = 683-177-2

| PubChem = 177014

| ChemSpiderID = 154159

| SMILES = O1c2c(OC1)c3c(cc2)[C@@]5([C@H](N(C3)C)c4cc6OCOc6cc4C[C@@H]5O)C

| InChI = 1/C21H21NO5/c1-21-14-3-4-15-19(27-10-24-15)13(14)8-22(2)20(21)12-7-17-16(25-9-26-17)5-11(12)6-18(21)23/h3-5,7,18,20,23H,6,8-10H2,1-2H3/t18-,20+,21-/m0/s1

| InChIKey = IQUGPRHKZNCHGC-TYPHKJRUBF

| StdInChI = 1S/C21H21NO5/c1-21-14-3-4-15-19(27-10-24-15)13(14)8-22(2)20(21)12-7-17-16(25-9-26-17)5-11(12)6-18(21)23/h3-5,7,18,20,23H,6,8-10H2,1-2H3/t18-,20+,21-/m0/s1

| StdInChIKey = IQUGPRHKZNCHGC-TYPHKJRUSA-N

}}

|Section2={{Chembox Properties

| C=21 | H=21 | N=1 | O=5

| Appearance =

| Density =

| MeltingPt =

| BoilingPt =

| Solubility = }}

|Section3={{Chembox Hazards

| MainHazards =

| FlashPt =

| AutoignitionPt = }}

}}

Corynoline is an acetylcholinesterase inhibitor isolated from Corydalis incisa.{{cite journal|pmid=12510831 |year=2002|last1=Kim|first1=DK|title=Inhibitory effect of corynoline isolated from the aerial parts of Corydalis incisa on the acetylcholinesterase|volume=25|issue=6|pages=817–9|journal=Archives of Pharmacal Research|doi=10.1007/bf02976997|s2cid=35891875}}

References