:Cu2+-exporting ATPase

{{Infobox enzyme

| Name = Cu²⁺-exporting ATPase

| EC_number = 3.6.3.4

| CAS_number =

| GO_code =

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Cu²⁺-exporting ATPase ({{EC number|3.6.3.4}}) is an enzyme with systematic name ATP phosphohydrolase (Cu²⁺-exporting).{{cite journal | vauthors = Vulpe C, Levinson B, Whitney S, Packman S, Gitschier J | title = Isolation of a candidate gene for Menkes disease and evidence that it encodes a copper-transporting ATPase | journal = Nature Genetics | volume = 3 | issue = 1 | pages = 7–13 | date = January 1993 | pmid = 8490659 | doi = 10.1038/ng0193-7 }}{{cite journal | vauthors = Petrukhin K, Lutsenko S, Chernov I, Ross BM, Kaplan JH, Gilliam TC | title = Characterization of the Wilson disease gene encoding a P-type copper transporting ATPase: genomic organization, alternative splicing, and structure/function predictions | journal = Human Molecular Genetics | volume = 3 | issue = 9 | pages = 1647–56 | date = September 1994 | pmid = 7833924 | doi = 10.1093/hmg/3.9.1647 }}{{cite journal | vauthors = Fagan MJ, Saier MH | title = P-type ATPases of eukaryotes and bacteria: sequence analyses and construction of phylogenetic trees | journal = Journal of Molecular Evolution | volume = 38 | issue = 1 | pages = 57–99 | date = January 1994 | pmid = 8151716 | doi = 10.1007/bf00175496 }} This enzyme catalyses the following chemical reaction

: ATP + H₂O + Cu²⁺_in $\backslash rightleftharpoons$ ADP + phosphate + Cu²⁺_out

This P-type ATPase undergoes covalent phosphorylation during the transport cycle.