:Dacemazine

{{Short description|Chemical compound}}

{{Drugbox

| Verifiedfields = changed

| verifiedrevid = 460112476

| IUPAC_name = 2-dimethylamino-1-phenothiazin-10-ylethanone

| image = Dacemazine.svg

| width =

| tradename =

| routes_of_administration =

| CAS_number_Ref = {{cascite|changed|??}}

| CAS_number = 518-61-6

| ATC_prefix = none

| PubChem = 68846

| ChEMBL_Ref = {{ebicite|changed|EBI}}

| ChEMBL = 2107547

| DrugBank_Ref = {{drugbankcite|correct|drugbank}}

| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}

| ChemSpiderID = 62079

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = 88D34UY0QI

| C=16 | H=16 | N=2 | O=1 | S=1

| smiles = O=C(N1c3c(Sc2c1cccc2)cccc3)CN(C)C

| StdInChI_Ref = {{stdinchicite|correct|chemspider}}

| StdInChI = 1S/C16H16N2OS/c1-17(2)11-16(19)18-12-7-3-5-9-14(12)20-15-10-6-4-8-13(15)18/h3-10H,11H2,1-2H3

| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}

| StdInChIKey = HKUCYAHWPVLPFN-UHFFFAOYSA-N

}}

Dacemazine (INN, also known as Ahistan and Histantine){{cite book | vauthors = Triggle DJ, Ganellin CR, MacDonald F |title=Dictionary of Pharmacological Agents |publisher=Chapman & Hall/CRC |location=Boca Raton |year=1996 |volume=1 |pages=711 |isbn=0-412-46630-9 |url=https://books.google.com/books?id=DeX7jgInYFMC}} Retrieved on August 2, 2008 through Google Book Search. is a phenothiazine derivative which acts as a histamine antagonist at the H₁ subtype. First described in 1951, it was never marketed as a drug on its own, although a combination of dacemazine and di-tert-butylnaphthalenesulfonate was sold as an antispasmodic and antitussive under the trade name Codopectyl. It was also assessed as a possible anticancer drug.{{cite journal | vauthors = Karolyhazy G, Havas I, Jansco G, Kapas L, Sellei C | title = [The anticarcinogenic effect of dimethylaminoacetyl-phentiazide (ahistan)] | language = ro | journal = Kiserletes Orvostudomany | volume = 4 | issue = 4 | pages = 260–2 | date = August 1952 | pmid = 13023855 }}