:Deoxyribonuclease (pyrimidine dimer)

{{Infobox enzyme

| Name = Deoxyribonuclease (pyrimidine dimer)

| EC_number = 3.1.25.1

| CAS_number = 66143-22-4

| GO_code =

| image =

| width =

| caption =

}}

Deoxyribonuclease (pyrimidine dimer) ({{EC number|3.1.25.1}}, endodeoxyribonuclease (pyrimidine dimer), bacteriophage T4 endodeoxyribonuclease V, T4 endonuclease V) is an enzyme.{{cite journal | vauthors = Braun AG, Radman M, Grossman L | title = Enzymatic repair of DNA: SITES OF HYDROLYSIS BY THE Escherichia coli endonuclease specific for pyrimidine dimers (correndonuclease II) | journal = Biochemistry | volume = 15 | issue = 18 | pages = 4116–20 | date = September 1976 | pmid = 786366 | doi = 10.1021/bi00663a031 }}{{cite journal | vauthors = Riazuddin S, Grossman L | title = Micrococcus luteus correndonucleases. II. Mechanism of action of two endonucleases specific for DNA containing pyrimidine dimers | journal = The Journal of Biological Chemistry | volume = 252 | issue = 18 | pages = 6287–93 | date = September 1977 | doi = 10.1016/S0021-9258(17)39953-2 | pmid = 330526 | doi-access = free }} This enzyme catalyses the following chemical reaction:

: Endonucleolytic cleavage near pyrimidine dimers to products with 5'-phosphate

This enzyme acts on a damaged strand, 5' from the damaged site.