:Dinitolmide
{{chembox
| Verifiedfields = changed
| verifiedrevid = 470638079
| ImageFile=Zoalene.png
| ImageSize=150px
| PIN = 2-Methyl-3,5-dinitrobenzamide
| OtherNames = 3,5-Dinitro-o-toluamide
Zoalene
|Section1={{Chembox Identifiers
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 2982
| InChI = 1/C8H7N3O5/c1-4-6(8(9)12)2-5(10(13)14)3-7(4)11(15)16/h2-3H,1H3,(H2,9,12)
| InChIKey = ZEFNOZRLAWVAQF-UHFFFAOYAL
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 472565
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C8H7N3O5/c1-4-6(8(9)12)2-5(10(13)14)3-7(4)11(15)16/h2-3H,1H3,(H2,9,12)
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = ZEFNOZRLAWVAQF-UHFFFAOYSA-N
| CASNo_Ref = {{cascite|correct|CAS}}
| CASNo=148-01-6
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = AOX68RY4TV
| PubChem=3092
| SMILES = O=[N+]([O-])c1cc(cc(C(=O)N)c1C)[N+]([O-])=O
}}
|Section2={{Chembox Properties
| Formula=C8H7N3O5
| MolarMass=225.16 g/mol
| Appearance=
| Density=
| MeltingPtF=351
| BoilingPt=
| Solubility=
}}
|Section6={{Chembox Pharmacology
| ATCvet = yes
| ATCCode_prefix = P51
| ATCCode_suffix = AX12
}}
|Section7={{Chembox Hazards
| MainHazards=
| FlashPt=noncombustible
| AutoignitionPt =
| PEL = none{{PGCH|0230}}
}}
}}
Dinitolmide (or zoalene) is a fodder additive for poultry, used to prevent coccidiosis infections.{{Cite journal
| doi = 10.1637/9572-101310-Reg.1
| last1 = Gerhold | first1 = R. W.
| last2 = Fuller | first2 = A. L.
| last3 = Lollis | first3 = L.
| last4 = Parr | first4 = C.
| last5 = McDougald | first5 = L. R.
| title = The Efficacy of Anticoccidial Products against Eimeria spp. in Northern Bobwhites
| journal = Avian Diseases
| volume = 55
| issue = 1
| pages = 59–64
| year = 2011
| pmid = 21500637
| s2cid = 30943649 }} It is sold under trade names such as Coccidine A, Coccidot, and Zoamix.
Dinitolmide is usually added to feed in doses of 125 ppm (preventive) or 250 ppm (curative). It is a broad-spectrum anticoccidial drug, preventing seven main strains of Eimeria coccidium. It leaves no residues in tissues.{{fact|date=December 2013}} It can be also used to prevent coccidiosis of domestic rabbits.
References
{{reflist}}
External links
- [http://dailymed.nlm.nih.gov/dailymed/archives/fdaDrugInfo.cfm?archiveid=15274 Zoamix - DailyMed]
Category:Nitrotoluene derivatives
{{antiinfective-drug-stub}}