:Fanetizole

{{Short description|Chemical compound}}

{{one source|date=July 2018}}

{{Drugbox

| verifiedrevid = 444137594

| IUPAC_name = 4-Phenyl-N-(2-phenylethyl)-1,3-thiazol-2-amine

| image = Fanetizole.svg

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| CAS_number = 79069-94-6

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| PubChem = 54339

| DrugBank_Ref = {{drugbankcite|correct|drugbank}}

| DrugBank =

| ChemSpiderID = 49083

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = BH48F620JA

| synonyms =

| C=17 | H=16 | N=2 | S=1

| SMILES = n1c(csc1NCCc2ccccc2)c3ccccc3

| StdInChI = 1S/C17H16N2S/c1-3-7-14(8-4-1)11-12-18-17-19-16(13-20-17)15-9-5-2-6-10-15/h1-10,13H,11-12H2,(H,18,19)

| StdInChIKey = WEEYMMXMBFJUAI-UHFFFAOYSA-N

}}

Fanetizole is a drug that has immunoregulating activity.{{cn|date=April 2023}}

Synthesis

Reaction of β-phenethylamine with ammonium thiocyanate gives the thiourea (2). Treatment of that product with phenacyl bromide produces fanetizole (3).Lombardino, J. G.; 1981, {{US Patent|4,307,106}}

: File:Fanetizole synthesis.svg{{clear-left}}

References

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{{Drugs for peptic ulcer and GORD}}

{{Histamine receptor modulators}}

{{Phenethylamines}}

Category:H2 receptor antagonists

Category:Phenethylamines

Category:Thiazoles