:Fruit bromelain

{{Infobox enzyme

| Name = Fruit bromelain

| EC_number = 3.4.22.33

| CAS_number = 9001-00-7

| GO_code =

| image =

| width =

| caption =

}}

Fruit bromelain ({{EC number|3.4.22.33}}, juice bromelain, ananase, Bromelase (a trademark), bromelin, extranase, pinase, pineapple enzyme, traumanase, fruit bromelain FA2) is an enzyme.{{cite journal | vauthors = Sasaki M, Kato T, Iida S | title = Antigenic determinant common to four kinds of thiol proteases of plant origin | journal = Journal of Biochemistry | volume = 74 | issue = 3 | pages = 635–7 | date = September 1973 | pmid = 4127920 }}{{cite journal | vauthors = Yamada F, Takahashi N, Murachi T | title = Purification and characterization of a proteinase from pineapple fruit, fruit bromelain FA2 | journal = Journal of Biochemistry | volume = 79 | issue = 6 | pages = 1223–34 | date = June 1976 | pmid = 956152 }}{{cite journal | vauthors = Ota S, Muta E, Katahira Y, Okamoto Y | title = Reinvestigation of fractionation and some properties of the proteolytically active components of stem and fruit bromelains | journal = Journal of Biochemistry | volume = 98 | issue = 1 | pages = 219–28 | date = July 1985 | pmid = 4044551 }}{{cite journal | vauthors = Rowan AD, Buttle DJ, Barrett AJ | title = The cysteine proteinases of the pineapple plant | journal = The Biochemical Journal | volume = 266 | issue = 3 | pages = 869–75 | date = March 1990 | pmid = 2327970 | pmc = 1131219 }} This enzyme catalyses the following chemical reaction

: Hydrolysis of proteins with broad specificity for peptide bonds. Bz-Phe-Val-Arg-NHMec is a good synthetic substrate

This enzyme is isolated from pineapple plant, Ananas comosus.