:INDO

{{About|a method in computational chemistry|the human INDO gene|Indoleamine 2,3-dioxygenase }}

INDO stands for Intermediate Neglect of Differential Overlap. It is a semi-empirical quantum chemistry method that is a development of the complete neglect of differential overlap (CNDO/2) method introduced by John Pople. Like CNDO/2 it uses zero-differential overlap for the two-electron integrals but not for integrals that are over orbitals centered on the same atom.{{cite journal | last1=Pople | first1=J. A. | last2=Beveridge | first2=D. L. | last3=Dobosh | first3=P. A. | title=Approximate Self‐Consistent Molecular‐Orbital Theory. V. Intermediate Neglect of Differential Overlap | journal=The Journal of Chemical Physics | publisher=AIP Publishing | volume=47 | issue=6 | date=1967-09-15 | issn=0021-9606 | doi=10.1063/1.1712233 | pages=2026–2033| bibcode=1967JChPh..47.2026P }}{{cite book | last = Pople | first = J. A. | author-link = John Pople |author2=D. Beveridge

| title = Approximate Molecular Orbital Theory | publisher = McGraw-Hill | year = 1970 }}

The method is now rarely used in its original form with some exceptions{{cite journal | last1=Abdulsattar | first1=Mudar A. | last2=Al-Bayati | first2=Khalil H. | title=Corrections and parametrization of semiempirical large unit cell method for covalent semiconductors | journal=Physical Review B | publisher=American Physical Society (APS) | volume=75 | issue=24 | date=2007-06-07 | issn=1098-0121 | doi=10.1103/physrevb.75.245201 | page=245201| bibcode=2007PhRvB..75x5201A }} but it is the basis for several other methods, such as MINDO, ZINDO and SINDO.