:Indolin-2-one monooxygenase

{{Short description|Class of enzymes}}

{{Infobox enzyme

| Name = Indolin-2-one monooxygenase

| EC_number = 1.14.13.138

| CAS_number =

| GO_code =

| image =

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| caption =

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Indolin-2-one monooxygenase ({{EC number|1.14.13.138}}, BX3 (gene), CYP71C2 (gene)) is an enzyme with systematic name indolin-2-one,NAD(P)H:oxygen oxidoreductase (3-hydroxylating).{{cite journal | vauthors = Frey M, Chomet P, Glawischnig E, Stettner C, Grün S, Winklmair A, Eisenreich W, Bacher A, Meeley RB, Briggs SP, Simcox K, Gierl A | title = Analysis of a chemical plant defense mechanism in grasses | journal = Science | volume = 277 | issue = 5326 | pages = 696–9 | date = August 1997 | pmid = 9235894 | doi = 10.1126/science.277.5326.696 }}{{cite journal | vauthors = Glawischnig E, Grün S, Frey M, Gierl A | title = Cytochrome P450 monooxygenases of DIBOA biosynthesis: specificity and conservation among grasses | journal = Phytochemistry | volume = 50 | issue = 6 | pages = 925–30 | date = March 1999 | pmid = 10385992 | doi = 10.1016/s0031-9422(98)00318-5 | bibcode = 1999PChem..50..925G }} This enzyme catalyses the following chemical reaction

: indolin-2-one + NAD(P)H + H+ + O2 \rightleftharpoons 3-hydroxyindolin-2-one + NAD(P)+ + H2O

Indolin-2-one monooxygenase is involved in the biosynthesis of protective and allelopathic benzoxazinoids in some plants.

References

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