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:MYO1F

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{Infobox_gene}}

Myosin-If is a protein that in humans is encoded by the MYO1F gene.{{cite journal |vauthors=Crozet F, el Amraoui A, Blanchard S, Lenoir M, Ripoll C, Vago P, Hamel C, Fizames C, Levi-Acobas F, Depetris D, Mattei MG, Weil D, Pujol R, Petit C | title = Cloning of the genes encoding two murine and human cochlear unconventional type I myosins | journal = Genomics | volume = 40 | issue = 2 | pages = 332–41 |date=Apr 1997 | pmid = 9119401 | doi =10.1006/geno.1996.4526 }}{{cite journal |vauthors=Hasson T, Skowron JF, Gilbert DJ, Avraham KB, Perry WL, Bement WM, Anderson BL, Sherr EH, Chen ZY, Greene LA, Ward DC, Corey DP, Mooseker MS, Copeland NG, Jenkins NA | title = Mapping of unconventional myosins in mouse and human | journal = Genomics | volume = 36 | issue = 3 | pages = 431–9 |date=Feb 1997 | pmid = 8884266 | doi = 10.1006/geno.1996.0488 | doi-access = free }}{{cite web | title = Entrez Gene: MYO1F myosin IF| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4542}}

It is expressed mainly in the immune system and might be involved in cell adhesion and motility.{{cite journal |vauthors=Kim SV, Mehal WZ, Dong X, Heinrich V, Pypaert M, Mellman I, Dembo M, Mooseker MS, Wu D, Flavell RA | title = Modulation of cell adhesion and motility in the immune system by Myo1f | journal = Science | volume = 314 | issue = 5796 | pages = 136–9 |date=October 2006 | pmid = 17023661 | doi = 10.1126/science.1131920 | bibcode = 2006Sci...314..136K | s2cid = 12479761 }} It is a candidate gene for (among other things) nonsyndromic deafness.{{cite journal |vauthors=Chen AH, Stephan DA, Hasson T, Fukushima K, Nelissen CM, Chen AF, Jun AI, Ramesh A, Van Camp G, Smith RJ | title = MYO1F as a candidate gene for nonsyndromic deafness, DFNB15 | journal = Arch. Otolaryngol. Head Neck Surg. | volume = 127 | issue = 8 | pages = 921–5 |date=August 2001 | pmid = 11493199 | doi = 10.1001/archotol.127.8.921 | doi-access = free }}

References

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Further reading

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  • {{cite journal |vauthors=Bement WM, Hasson T, Wirth JA, etal |title=Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=91 |issue= 14 |pages= 6549–53 |year= 1994 |pmid= 8022818 |doi=10.1073/pnas.91.14.6549 | pmc=44240 |bibcode=1994PNAS...91.6549B |doi-access=free }}
  • {{cite journal |vauthors=Krugmann S, Anderson KE, Ridley SH, etal |title=Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices |journal=Mol. Cell |volume=9 |issue= 1 |pages= 95–108 |year= 2002 |pmid= 11804589 |doi=10.1016/S1097-2765(02)00434-3 |doi-access=free }}
  • {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
  • {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |doi-access= free }}
  • {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
  • {{cite journal |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |bibcode=2005Natur.437.1173R |s2cid=4427026 }}
  • {{cite journal |vauthors=Olsen JV, Blagoev B, Gnad F, etal |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 |s2cid=7827573 |doi-access=free }}

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{{Cytoskeletal_proteins}}

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