:Methane monooxygenase (particulate)

{{Infobox enzyme

| Name = Methane monooxygenase (particulate)

| EC_number = 1.14.18.3

| CAS_number =

| GO_code =

| image = 1yew.jpg

| width = 270

| caption = Particulate methane monooxygenase hexa-heterotrimer, Methylococcus capsulatus

}}

Methane monooxygenase (particulate) ({{EC number|1.14.18.3}}) is an enzyme with systematic name methane,quinol:oxygen oxidoreductase.{{cite journal | vauthors = Shiemke AK, Cook SA, Miley T, Singleton P | title = Detergent solubilization of membrane-bound methane monooxygenase requires plastoquinol analogs as electron donors | journal = Archives of Biochemistry and Biophysics | volume = 321 | issue = 2 | pages = 421–8 | date = August 1995 | pmid = 7646068 | doi = 10.1006/abbi.1995.1413 }}{{cite journal | vauthors = Basu P, Katterle B, Andersson KK, Dalton H | title = The membrane-associated form of methane mono-oxygenase from Methylococcus capsulatus (Bath) is a copper/iron protein | journal = The Biochemical Journal | volume = 369 | issue = Pt 2 | pages = 417–27 | date = January 2003 | pmid = 12379148 | pmc = 1223091 | doi = 10.1042/BJ20020823 }}{{cite journal | vauthors = Kitmitto A, Myronova N, Basu P, Dalton H | title = Characterization and structural analysis of an active particulate methane monooxygenase trimer from Methylococcus capsulatus (Bath) | journal = Biochemistry | volume = 44 | issue = 33 | pages = 10954–65 | date = August 2005 | pmid = 16101279 | doi = 10.1021/bi050820u }}{{cite journal | vauthors = Balasubramanian R, Rosenzweig AC | title = Structural and mechanistic insights into methane oxidation by particulate methane monooxygenase | journal = Accounts of Chemical Research | volume = 40 | issue = 7 | pages = 573–80 | date = July 2007 | pmid = 17444606 | doi = 10.1021/ar700004s }} This enzyme catalyses the following chemical reaction

: methane + quinol + O₂ $\backslash rightleftharpoons$ methanol + quinone + H₂O

Methane monooxygenase contains copper. It is membrane-bound enzyme present in methanotrophs.