:Michaelis–Becker reaction

{{Short description|Chemical reaction}}

The Michaelis–Becker reaction is the reaction of a hydrogen (thio)phosphonate with a base, followed by a nucleophilic substitution of phosphorus on a haloalkane, to give an alkyl (thio)phosphonate.{{cite book|title=Sulfur in Organic and Inorganic Chemistry|volume=1|editor-first=Alexander|editor-last=Senning|year=1971|publisher=Marcel Dekker|location=New York|lccn=70-154612|isbn=0-8247-1615-9|first=Lucreţia|last=Almasi|chapter=The Sulfur–Phosphorus Bond|page=56}} Yields of this reaction are often lower than the corresponding Michaelis–Arbuzov reaction.Fletcher, M.D. Organophosphorus Reagents; Murphy, P.J. Ed.; University Press: Oxford, 2002; pp. 185.{{cite book | url = https://books.google.com/books?id=mBfS8kNZA5gC&pg=PA185 | isbn = 978-0-19-850262-3 | title = Organophosphorus reagents: a practical approach in chemistry | publisher = Oxford University Press | author1 = Murphy, Dr. Patrick J | year = 2004}}

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