:Milker's nodule
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| caption = Human skin infection of paravaccinia virus.
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Milker's nodules are a cutaneous condition that is most commonly transmitted from the udders of infected cows.{{cite book |author=James, William D. |author2=Berger, Timothy G.|title=Andrews' Diseases of the Skin: clinical Dermatology |publisher=Saunders Elsevier |year=2006 |isbn=978-0-7216-2921-6 |display-authors=etal}}{{rp|393}}{{cite book |author=Rapini, Ronald P. |author2=Bolognia, Jean L. |author3=Jorizzo, Joseph L. |title=Dermatology: 2-Volume Set |publisher=Mosby |location=St. Louis |year=2007 |isbn=978-1-4160-2999-1 }} Milker's nodule is caused by Paravaccinia virus. The disease in humans is nearly identical to Orf.{{cite journal |vauthors=Espósito AC, Jorge MF, Marques ME, Abbade LP |date=November–December 2017 |title=Milker's nodules: classic histological findings |journal=An Bras Dermatol |volume=92 |issue=6 |pages=838–840 |doi=10.1590/abd1806-4841.20176923 |pmc=5786401 |pmid=29364443}}
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Pathogen
Milker's nodules is a zoonotic dermatosis. It was caused by double-stranded DNA virus of the Parapoxvirus genus. Parapoxvirus usually presents in the saliva, nasal secretions, and in lesions over the udder, trunk, and limbs of affected bovine cattle. It may transmitted by direct or indirect contact of lesion.{{Cite journal|last=Jayasree|first=Puravoor|last2=Kaliyadan|first2=Feroze|last3=Abraham|first3=Ranjima|date=2019-10-23|title=Milker’s Nodule|url=https://jamanetwork.com/journals/jamadermatology/fullarticle/2753264|journal=JAMA Dermatology|language=en|doi=10.1001/jamadermatol.2019.3248|url-access=subscription}}
See also
References
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{{Viral cutaneous conditions}}
Category:Virus-related cutaneous conditions
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