:N-succinylornithine carbamoyltransferase
{{Infobox enzyme
| Name = N-succinylornithine carbamoyltransferase
| EC_number = 2.1.3.11
| CAS_number =
| GO_code =
| image =
| width =
| caption =
}}
N-succinylornithine carbamoyltransferase ({{EC number|2.1.3.11}}, succinylornithine transcarbamylase, N-succinyl-L-ornithine transcarbamylase, SOTCase) is an enzyme with systematic name carbamoyl phosphate:N2-succinyl-L-ornithine carbamoyltransferase.{{cite journal | vauthors = Shi D, Morizono H, Cabrera-Luque J, Yu X, Roth L, Malamy MH, Allewell NM, Tuchman M | title = Structure and catalytic mechanism of a novel N-succinyl-L-ornithine transcarbamylase in arginine biosynthesis of Bacteroides fragilis | journal = The Journal of Biological Chemistry | volume = 281 | issue = 29 | pages = 20623–31 | date = July 2006 | pmid = 16704984 | doi = 10.1074/jbc.M601229200 | doi-access = free }}{{cite journal | vauthors = Shi D, Yu X, Cabrera-Luque J, Chen TY, Roth L, Morizono H, Allewell NM, Tuchman M | title = A single mutation in the active site swaps the substrate specificity of N-acetyl-L-ornithine transcarbamylase and N-succinyl-L-ornithine transcarbamylase | journal = Protein Science | volume = 16 | issue = 8 | pages = 1689–99 | date = August 2007 | pmid = 17600144 | pmc = 2203365 | doi = 10.1110/ps.072919907 }} This enzyme catalyses the following chemical reaction
: carbamoyl phosphate + N2-succinyl-L-ornithine phosphate + N-succinyl-L-citrulline
This enzyme is specific for N-succinyl-L-ornithine.
References
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External links
- {{MeshName|N-succinylornithine+carbamoyltransferase}}
{{One carbon transferases}}
{{Enzymes}}
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