:Oxepin-CoA hydrolase

{{Short description|Class of enzymes}}

{{Infobox enzyme

| Name = Oxepin-CoA hydrolase

| EC_number = 3.7.1.16

| CAS_number =

| GO_code =

| image =

| width =

| caption =

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Oxepin-CoA hydrolase ({{EC number|3.7.1.16}}, paaZ (gene)) is an enzyme with systematic name 2-oxepin-2(3H)-ylideneacetyl-CoA hydrolyase.{{cite journal | vauthors = Ferrández A, Miñambres B, García B, Olivera ER, Luengo JM, García JL, Díaz E | title = Catabolism of phenylacetic acid in Escherichia coli. Characterization of a new aerobic hybrid pathway | journal = The Journal of Biological Chemistry | volume = 273 | issue = 40 | pages = 25974–86 | date = October 1998 | pmid = 9748275 | doi = 10.1074/jbc.273.40.25974 | doi-access = free }}{{cite journal | vauthors = Park SJ, Lee SY | title = Identification and characterization of a new enoyl coenzyme A hydratase involved in biosynthesis of medium-chain-length polyhydroxyalkanoates in recombinant Escherichia coli | journal = Journal of Bacteriology | volume = 185 | issue = 18 | pages = 5391–7 | date = September 2003 | pmid = 12949091 | pmc = 193764 | doi = 10.1128/jb.185.18.5391-5397.2003 | url = http://koasas.kaist.ac.kr/bitstream/10203/21887/1/int119.pdf }}{{cite journal | vauthors = Ismail W, El-Said Mohamed M, Wanner BL, Datsenko KA, Eisenreich W, Rohdich F, Bacher A, Fuchs G | title = Functional genomics by NMR spectroscopy. Phenylacetate catabolism in Escherichia coli | journal = European Journal of Biochemistry | volume = 270 | issue = 14 | pages = 3047–54 | date = July 2003 | pmid = 12846838 | doi = 10.1046/j.1432-1033.2003.03683.x | doi-access = free }}{{cite journal | vauthors = Teufel R, Mascaraque V, Ismail W, Voss M, Perera J, Eisenreich W, Haehnel W, Fuchs G | title = Bacterial phenylalanine and phenylacetate catabolic pathway revealed | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 107 | issue = 32 | pages = 14390–5 | date = August 2010 | pmid = 20660314 | pmc = 2922514 | doi = 10.1073/pnas.1005399107 | doi-access = free }} This enzyme catalyses the following chemical reaction

: 2-oxepin-2(3H)-ylideneacetyl-CoA + H₂O $\backslash rightleftharpoons$ 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde

The enzyme is present in bacteria Escherichia coli.