:Pentalenic acid synthase

{{Infobox enzyme

| Name = Pentalenic acid synthase

| EC_number = 1.14.15.11

| CAS_number =

| GO_code =

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Pentalenic acid synthase ({{EC number|1.14.15.11}}, CYP105D7, sav7469 (gene)) is an enzyme with systematic name {{chem name|1-deoxypentalenate,reduced ferredoxin:O2 oxidoreductase}}.{{cite journal | vauthors = Takamatsu S, Xu LH, Fushinobu S, Shoun H, Komatsu M, Cane DE, Ikeda H | title = Pentalenic acid is a shunt metabolite in the biosynthesis of the pentalenolactone family of metabolites: hydroxylation of 1-deoxypentalenic acid mediated by CYP105D7 (SAV_7469) of Streptomyces avermitilis | journal = The Journal of Antibiotics | volume = 64 | issue = 1 | pages = 65–71 | date = January 2011 | pmid = 21081950 | pmc = 3030646 | doi = 10.1038/ja.2010.135 }} This enzyme catalyses the following chemical reaction

: 1-deoxypentalenate + reduced ferredoxin + O2 \rightleftharpoons pentalenate + oxidized ferredoxin + H2O

Pentalenic acid synthase is a heme-thiolate enzyme (P-450).

References

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