:Principle of least motion

In organic chemistry, the principle of least motion is the hypothesis that when multiple species with different nuclear structures could theoretically form as products of a given chemical reaction, the more likely to form tends to be the one requiring the least amount of change in nuclear structure or the smallest change in nuclear positions.{{Cite journal| author =Hine J | title = The principle of least nuclear motion | journal = Advances in Physical Organic Chemistry | volume = 15 | pages = 1–61 | year = 1977 | doi = 10.1016/S0065-3160(08)60117-3}}