:Procollagen C-endopeptidase

{{Infobox enzyme

| Name = Procollagen C-endopeptidase

| EC_number = 3.4.24.19

| CAS_number = 68651-95-6

| GO_code =

| image =

| width =

| caption =

}}

Procollagen C-endopeptidase ({{EC number|3.4.24.19}}, procollagen C-terminal proteinase, carboxyprocollagen peptidase, procollagen C-terminal peptidase, procollagen C-proteinase, procollagen carboxypeptidase, procollagen carboxy-terminal proteinase, procollagen peptidase) is an enzyme.{{cite journal | vauthors = Hojima Y, van der Rest M, Prockop DJ | title = Type I procollagen carboxyl-terminal proteinase from chick embryo tendons. Purification and characterization | journal = The Journal of Biological Chemistry | volume = 260 | issue = 29 | pages = 15996–6003 | date = December 1985 | pmid = 3905801 }}{{cite journal | vauthors = Kessler E, Adar R | title = Type I procollagen C-proteinase from mouse fibroblasts. Purification and demonstration of a 55-kDa enhancer glycoprotein | journal = European Journal of Biochemistry | volume = 186 | issue = 1-2 | pages = 115–21 | date = December 1989 | pmid = 2689170 | doi = 10.1111/j.1432-1033.1989.tb15184.x | doi-access = free }} This enzyme catalyses the following chemical reaction

: Cleavage of the C-terminal propeptide at Ala-Asp in type I and II procollagens and at Arg-Asp in type III

This endopeptidase belongs to the peptidase family M12 (astacin family).