:Putidaredoxin—NAD+ reductase

{{Infobox enzyme

| Name = Putidaredoxin—NAD+ reductase

| EC_number = 1.18.1.5

| CAS_number =

| GO_code =

| image =

| width =

| caption =

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Putidaredoxin—NAD+ reductase ({{EC number|1.18.1.5}}, putidaredoxin reductase, camA (gene)) is an enzyme with systematic name putidaredoxin:NAD+ oxidoreductase.{{cite journal | vauthors = Roome PW, Philley JC, Peterson JA | title = Purification and properties of putidaredoxin reductase | journal = The Journal of Biological Chemistry | volume = 258 | issue = 4 | pages = 2593–8 | date = February 1983 | pmid = 6401738 }}{{cite journal | vauthors = Koga H, Yamaguchi E, Matsunaga K, Aramaki H, Horiuchi T | title = Cloning and nucleotide sequences of NADH-putidaredoxin reductase gene (camA) and putidaredoxin gene (camB) involved in cytochrome P-450cam hydroxylase of Pseudomonas putida | journal = Journal of Biochemistry | volume = 106 | issue = 5 | pages = 831–6 | date = November 1989 | pmid = 2613690 }}{{cite journal | vauthors = Peterson JA, Lorence MC, Amarneh B | title = Putidaredoxin reductase and putidaredoxin. Cloning, sequence determination, and heterologous expression of the proteins | journal = The Journal of Biological Chemistry | volume = 265 | issue = 11 | pages = 6066–73 | date = April 1990 | pmid = 2180940 }}{{cite journal | vauthors = Sevrioukova IF, Poulos TL | title = Putidaredoxin reductase, a new function for an old protein | journal = The Journal of Biological Chemistry | volume = 277 | issue = 28 | pages = 25831–9 | date = July 2002 | pmid = 12011076 | doi = 10.1074/jbc.m201110200 | doi-access = free }}{{cite journal | vauthors = Sevrioukova IF, Garcia C, Li H, Bhaskar B, Poulos TL | title = Crystal structure of putidaredoxin, the [2Fe-2S] component of the P450cam monooxygenase system from Pseudomonas putida | journal = Journal of Molecular Biology | volume = 333 | issue = 2 | pages = 377–92 | date = October 2003 | pmid = 14529624 | doi = 10.1016/j.jmb.2003.08.028 }}{{cite journal | vauthors = Sevrioukova IF, Li H, Poulos TL | title = Crystal structure of putidaredoxin reductase from Pseudomonas putida, the final structural component of the cytochrome P450cam monooxygenase | journal = Journal of Molecular Biology | volume = 336 | issue = 4 | pages = 889–902 | date = February 2004 | pmid = 15095867 | doi = 10.1016/j.jmb.2003.12.067 }}{{cite journal | vauthors = Smith N, Mayhew M, Holden MJ, Kelly H, Robinson H, Heroux A, Vilker VL, Gallagher DT | title = Structure of C73G putidaredoxin from Pseudomonas putida | journal = Acta Crystallographica Section D | volume = 60 | issue = Pt 5 | pages = 816–22 | date = May 2004 | pmid = 15103126 | doi = 10.1107/s0907444904003348 | url = https://zenodo.org/record/1236096/files/article.pdf }} This enzyme catalyses the following chemical reaction

: reduced putidaredoxin + NAD+ \rightleftharpoons oxidized putidaredoxin + NADH + H+

Putidaredoxin—NAD+ reductase requires FAD.

References

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