:Pyrrole-2-carboxylate monooxygenase

{{Short description|Class of enzymes}}

{{Infobox enzyme

| Name = Pyrrole-2-carboxylate monooxygenase

| EC_number = 1.14.13.130

| CAS_number =

| GO_code =

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Pyrrole-2-carboxylate monooxygenase ({{EC number|1.14.13.130}}, pyrrole-2-carboxylate oxygenase) is an enzyme with systematic name pyrrole-2-carboxylate,NADH:oxygen oxidoreductase (5-hydroxylating).{{cite journal | vauthors = Hormann K, Andreesen JR | title = Purification and characterization of a pyrrole-2-carboxylate oxygenase from Arthrobacter strain Py1 | journal = Biological Chemistry Hoppe-Seyler | volume = 375 | issue = 3 | pages = 211–8 | date = March 1994 | pmid = 8011178 }}{{cite journal | vauthors = Becker D, Schräder T, Andreesen JR | title = Two-component flavin-dependent pyrrole-2-carboxylate monooxygenase from Rhodococcus sp | journal = European Journal of Biochemistry | volume = 249 | issue = 3 | pages = 739–47 | date = November 1997 | pmid = 9395321 | doi = 10.1111/j.1432-1033.1997.t01-1-00739.x | doi-access = free }} This enzyme catalyses the following chemical reaction

: pyrrole-2-carboxylate + NADH + H+ + O2 \rightleftharpoons 5-hydroxypyrrole-2-carboxylate + NAD+ + H2O

Pyrrole-2-carboxylate monooxygenase is a flavoprotein (FAD).

References

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