:SpoIVB peptidase

{{Infobox enzyme

| Name = SpoIVB peptidase

| EC_number = 3.4.21.116

| CAS_number = 296241-18-4

| GO_code =

| image =

| width =

| caption =

}}

SpoIVB peptidase ({{EC number|3.4.21.116}}, sporulation factor IV B protease) is an enzyme.{{cite journal | vauthors = Wakeley PR, Dorazi R, Hoa NT, Bowyer JR, Cutting SM | title = Proteolysis of SpolVB is a critical determinant in signalling of Pro-sigmaK processing in Bacillus subtilis | journal = Molecular Microbiology | volume = 36 | issue = 6 | pages = 1336–48 | date = June 2000 | pmid = 10931284 | doi = 10.1046/j.1365-2958.2000.01946.x | doi-access = free }}{{cite journal | vauthors = Hoa NT, Brannigan JA, Cutting SM | title = The PDZ domain of the SpoIVB serine peptidase facilitates multiple functions | journal = Journal of Bacteriology | volume = 183 | issue = 14 | pages = 4364–73 | date = July 2001 | pmid = 11418578 | pmc = 95327 | doi = 10.1128/jb.183.14.4364-4373.2001 }}{{cite journal | vauthors = Hoa NT, Brannigan JA, Cutting SM | title = The Bacillus subtilis signaling protein SpoIVB defines a new family of serine peptidases | journal = Journal of Bacteriology | volume = 184 | issue = 1 | pages = 191–9 | date = January 2002 | pmid = 11741860 | pmc = 134772 | doi = 10.1128/jb.184.1.191-199.2002 }}{{cite journal | vauthors = Dong TC, Cutting SM | title = SpoIVB-mediated cleavage of SpoIVFA could provide the intercellular signal to activate processing of Pro-sigmaK in Bacillus subtilis | journal = Molecular Microbiology | volume = 49 | issue = 5 | pages = 1425–34 | date = September 2003 | pmid = 12940997 | doi = 10.1046/j.1365-2958.2003.03651.x | doi-access = free }} This enzyme catalyses the following chemical reaction

: Self-cleaves Val52-Asn53, Ala62-Phe63 and Val74-Thr75 at the N-terminus of SpoIVB

This enzyme participates in gene expression during the later stages of spore formation in Bacillus subtilis.