:Stratum corneum chymotryptic enzyme

{{Infobox enzyme

| Name = Stratum corneum chymotryptic enzyme

| EC_number = 3.4.21.117

| CAS_number = 155215-90-0

| GO_code =

| image =

| width =

| caption =

}}

Stratum corneum chymotryptic enzyme ({{EC number|3.4.21.117}}, kallikrein 7, SCCE, KLK7, PRSS6, hK7) is an enzyme.{{cite journal | vauthors = Skytt A, Strömqvist M, Egelrud T | title = Primary substrate specificity of recombinant human stratum corneum chymotryptic enzyme | journal = Biochemical and Biophysical Research Communications | volume = 211 | issue = 2 | pages = 586–9 | date = June 1995 | pmid = 7794273 | doi = 10.1006/bbrc.1995.1853 }}{{cite journal | vauthors = Egelrud T | title = Purification and preliminary characterization of stratum corneum chymotryptic enzyme: a proteinase that may be involved in desquamation | journal = The Journal of Investigative Dermatology | volume = 101 | issue = 2 | pages = 200–4 | date = August 1993 | pmid = 8393902 | doi = 10.1111/1523-1747.ep12363804 | doi-access = }}{{cite journal | vauthors = Hansson L, Strömqvist M, Bäckman A, Wallbrandt P, Carlstein A, Egelrud T | title = Cloning, expression, and characterization of stratum corneum chymotryptic enzyme. A skin-specific human serine proteinase | journal = The Journal of Biological Chemistry | volume = 269 | issue = 30 | pages = 19420–6 | date = July 1994 | pmid = 8034709 }}{{cite journal | vauthors = Yousef GM, Scorilas A, Magklara A, Soosaipillai A, Diamandis EP | title = The KLK7 (PRSS6) gene, encoding for the stratum corneum chymotryptic enzyme is a new member of the human kallikrein gene family - genomic characterization, mapping, tissue expression and hormonal regulation | journal = Gene | volume = 254 | issue = 1-2 | pages = 119–28 | date = August 2000 | pmid = 10974542 | doi = 10.1016/S0378-1119(00)00280-8 }}{{cite journal | vauthors = Vasilopoulos Y, Cork MJ, Murphy R, Williams HC, Robinson DA, Duff GW, Ward SJ, Tazi-Ahnini R | title = Genetic association between an AACC insertion in the 3'UTR of the stratum corneum chymotryptic enzyme gene and atopic dermatitis | journal = The Journal of Investigative Dermatology | volume = 123 | issue = 1 | pages = 62–6 | date = July 2004 | pmid = 15191543 | doi = 10.1111/j.0022-202X.2004.22708.x | doi-access = free }} This enzyme catalyses the following chemical reaction

: Cleavage of proteins with aromatic side chains in the P1 position

This enzyme has wide substrate specificity.