:Sulfacytine

{{Short description|Chemical compound}}

{{Drugbox

| IUPAC_name = 4-Amino-N-(1-ethyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzene-1-sulfonamide

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| routes_of_administration = Oral

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| CAS_number = 17784-12-2

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| PubChem = 5322

| PubChemSubstance = 46505483

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| DrugBank = DB01298

| ChemSpiderID = 5131

| UNII = T795873AJP

| ChEMBL = 1201056

| synonyms = {{unbulletedlist|1-Ethyl N4-sulfanilylcytosine | 1-Ethyl-N-sulfanilylcytosine | N-Sulfanilyl-l-ethylcytosine | Sulfacitina [inn-spanish] | Sulfacitinum [inn-latin] }}

| C=12 | H=14 | N=4 | O=3 | S=1

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| SMILES = CCN1C=CC(NS(=O)(=O)C2=CC=C(N)C=C2)=NC1=O

| StdInChI = InChI=1S/C12H14N4O3S/c1-2-16-8-7-11(14-12(16)17)15-20(18,19)10-5-3-9(13)4-6-10/h3-8H,2,13H2,1H3,(H,14,15,17)

| StdInChIKey = SIBQAECNSSQUOD-UHFFFAOYSA-N

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Sulfacytine is a short-acting sulfonamide antibiotic,{{DrugBank|DB01298}} taken orally for treatment against bacterial infections. Sulfonamides, as a group of antibiotics, work by inhibiting the bacterial synthesis of folate. In 2006, the drug was discontinued.Federal Register

[https://www.fda.gov/downloads/advisorycommittees/committeesmeetingmaterials/drugs/pharmacycompoundingadvisorycommittee/ucm433804.pdf Section: Food and Drug Administration] [Docket No. 2006N–0222] Merck & Co., Inc., et al.; Withdrawal of Approval of 65 New Drug Applications and 52 Abbreviated New Drug Applications] Vol. 71, No. 116 / Friday, June 16, 2006. p34941FDA Orange book. [http://www.accessdata.fda.gov/scripts/cder/ob/docs/obdetail.cfm?Appl_No=017569&TABLE1=OB_Disc Sulfacytine] Page accessed May 12, 2015

References