:Talk:Children's Hospital of Philadelphia
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{{DYK talk|30 August|2004|entry=...that the Children's Hospital of Philadelphia pioneered the use of incubators for newborn intensive care?}}
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Proposed merge of [[The Voice (CHOP)]] into [[Children's Hospital of Philadelphia]]
A department within CHOP. Andrew nyr (talk, contribs) 19:43, 30 April 2020 (UTC)
COI edit requests
{{edit COI}}
Hi! I'm a COI editor for CHOP, a client of my employer, Porter Novelli. Requesting some updates to this article:
- In the infobox, lead, and at the beginning of "Facilities", update the number of beds from 594 to 692.{{cite web |title=Hospital and CHOP Care Network Statistics |url=https://www.chop.edu/about-us/annual-report-of-our-financials/hospital-statistics |website=The Children's Hospital of Philadelphia |access-date=March 3, 2025 |language=en}} (I know primary sources are sometimes acceptable for certain fundamental info; if an independent source is required, Becker's Hospital Review has an older (but still more recent than the currently used) figure of 667.{{cite news |last1=Gamble |first1=Molly |title=30 largest children's hospitals |url=https://www.beckershospitalreview.com/rankings-and-ratings/largest-childrens-hospitals-2024.html |access-date=August 8, 2024 |work=Becker's Hospital Review |date=February 14, 2024 |language=en-gb}})
: {{Done}}, I am not sure this needs a exact number as opposed to an approximation given that this changes rapidly, but I'm happy to take a primary source here. Rusalkii (talk) 19:27, 18 March 2025 (UTC)
- In the lead, delete "on the campus of the University of Pennsylvania". This is inaccurate; the assertion two paragraphs later that "The hospital is located next to the University of Pennsylvania" is correct. ("Fourth hospital, since 1974" in "History" also confirms this.)
: {{Not done for now}} The statement in the history section does say it's next to rather than on the campus, but that paragraph is entirely uncited. I also don't see anything in the source for the last paragraph of the lead about the location on or off campus. Happy to make this change but I'd like to see a source. Rusalkii (talk) 19:27, 18 March 2025 (UTC)
::{{replyto|Rusalkii}} Finding a media source for this was surprisingly tricky. How about this from Penn? "The Children's Hospital of Philadelphia (CHOP), the first pediatric hospital in the United States, is a modern, 430-bed tertiary center located adjacent to HUP" [The Hospital of the University of Pennsylvania].{{cite web |title=Penn Medicine Campus |url=https://www.pennmedicine.org/departments-and-centers/anesthesiology-and-critical-care/education-and-training/residency-program/campus |website=Penn Medicine |access-date=19 March 2025}} And thanks for your help! Mary Gaulke (talk) 18:59, 19 March 2025 (UTC)
:::Happy to take a primary source here, seems like a straightforward WP:ABOUTSELF. I don't see how that confirms that it isn't on campus, though, without a source saying that HUP is also not on campus (and not near it, either). Rusalkii (talk) 19:19, 19 March 2025 (UTC)
:::Do you have a map of the campus clearly showing boundaries that we could locate the hospital on? We may also be able to write around this altogether and say something like "located at such and such a place" without referencing the campus in any way; given that these location claims are currently unsourced I see no reason not to remove them if there's any doubt. Rusalkii (talk) 19:25, 19 March 2025 (UTC)
::::Here are maps from the University of Pennsylvania (UPenn) [https://facilities.upenn.edu/sites/default/files/pdfs/penn_campus_map_download.pdf PDF] and [https://facilities.upenn.edu/maps web link]. Here is a map from CHOP [https://www.chop.edu/philadelphia-campus/campus-maps website] and [https://www.chop.edu/sites/default/files/locations-chop-main-campus-map.pdf PDF]. UPenn owns property bordering and adjacent to CHOP properties. You could say the UPenn properties surround the CHOP's main hospital and facilities, but it's a grey area. cc {{U|MaryGaulke}} — 🌊PacificDepths (talk) 06:46, 12 May 2025 (UTC)
- In the lead, update
::more than one million outpatient and inpatient visits annually.{{cite journal | url=http://doi.org/10.1016/j.ajic.2020.04.008 | doi=10.1016/j.ajic.2020.04.008 | title=A strategy for expanding infection prevention resources to support organizational growth | year=2020 | last1=Smathers | first1=Sarah A. | last2=Sammons | first2=Julia S. | journal=American Journal of Infection Control | volume=48 | issue=9 | pages=975–981 | pmid=32305429 | s2cid=216031522 }}
:to
::more than 1.6 million outpatient and inpatient visits annually.
: {{Done}} Rusalkii (talk) 19:27, 18 March 2025 (UTC)
- Also in the lead, update
::CHOP has been ranked as the best children's hospital in the United States by U.S. News & World Report{{Cite web|url=https://health.usnews.com/best-hospitals/area/pa/childrens-hospital-of-philadelphia-6231730|archive-url=https://web.archive.org/web/20200214155404/https://health.usnews.com/best-hospitals/area/pa/childrens-hospital-of-philadelphia-6231730|url-status=dead|archive-date=2020-02-14|title=Children's Hospital of Philadelphia in Philadelphia, PA – Rankings, Ratings & Photos {{!}} US News Best Children's Hospitals Rankings|date=2020-02-14|access-date=2020-02-14}} and Parents Magazine{{Cite web|url=https://www.parents.com/health/doctors/10-best-childrens-hospitals/|title=20 Top Children's Hospitals in Innovation and Technology|website=Parents|language=EN|access-date=2020-02-14|archive-date=2020-06-19|archive-url=https://web.archive.org/web/20200619175752/https://www.parents.com/health/doctors/10-best-childrens-hospitals/|url-status=live}} since 2020. {{asof|2020|post=,}} it was ranked number one in the nation by U.S. News & World Report for three out of ten specialties.[http://health.usnews.com/best-hospitals/children%27s-hospital-of-philadelphia-6231730 "Best Children's Hospitals: General Pediatrics"] {{Webarchive|url=https://web.archive.org/web/20120601014748/http://health.usnews.com/best-hospitals/children's-hospital-of-philadelphia-6231730 |date=2012-06-01 }} U.S. News & World Report, Accessed 9 June 2012.
:to
::CHOP has been ranked as one of the best children's hospitals in the United States by U.S. News & World Report since 2007.{{cite news |last1=Hitti |first1=Miranda |title=Philadelphia Children's Hospital Tops List |url=https://www.cbsnews.com/news/philadelphia-childrens-hospital-tops-list/ |access-date=December 24, 2024 |work=CBS News |date=August 27, 2007}}{{cite news |last1=George |first1=John |title=CHOP once again ranks among 10 best children's hospitals in the nation, according to U.S. News |url=https://www.bizjournals.com/philadelphia/news/2024/10/08/childrens-hospital-of-philadelphia-us-news-ranking.html |access-date=January 14, 2025 |work=Philadelphia Business Journal |date=October 8, 2024}} {{asof|2024|post=,}} it was ranked number one in the nation by U.S. News & World Report for two out of 11 specialties.
:I suggest cutting the Parents Magazine ranking, since the publication no longer ranks children's hospitals.
:: {{Partly done}} Parent's magazine removed, specialty ranking updated. However, I don't love the "ranked as best since 2007" phrasing, since what we have is (1) it being ranked as best in 2007, and (2) a 2024 source saying that it was ranked as one of the ten best that year, with no ordering, had been 4th the previous year, and "made the Honor Roll every year since U.S. News first started publishing it in 2009". Rewriting this as "CHOP has been ranked among the best ten children's hospitals in the United States by U.S. News & World Report since 2009". If you can find a 2008 ranking I am happy to adjust to "since 2007". Rusalkii (talk) 19:27, 18 March 2025 (UTC)
- Add to end of lead:
::CHOP has 19,722 employees and reported $4.54 billion in revenue in fiscal year 2024.{{cite news |last1=Brubaker |first1=Harold |title=Most Philadelphia nonprofit health systems had improved financial results in fiscal 2024 |url=https://www.inquirer.com/health/philadelphia-nonprofit-health-systems-financial-results-2024-20241107.html |access-date=March 3, 2025 |work=The Philadelphia Inquirer |date=November 7, 2024 |language=en}}
: {{Not done for now}} as a general rule, the lead should summarize the body of the article. (WP:LEAD). This does seem relevant, so I'd just add it myself somewhere in the body, but I'm not sure where a natural place would be. The organization is overall a little wonky - probably somewhere in "About", which is kind of a terrible section name but I don't have a better suggestion off the top of my head. Rusalkii (talk) 19:27, 18 March 2025 (UTC)
::{{replyto|Rusalkii}} Perhaps "Operations" is a better alternative to "About"? Mary Gaulke (talk) 19:01, 19 March 2025 (UTC)
:::So I just skimmed through some other hospital articles, and it looks like a lot of them that have this kind of section in fact title it "About", it seems to be much more common than any other name. I'm not sure if there's a reason for that but I suppose in the absence of any reason to retitle it other than "ugh" I'be changed my mind and am inclined towards keeping as is. Rusalkii (talk) 19:37, 19 March 2025 (UTC)
- The subsections of the "History" section use the word "hospital" in a confusing way – first hospital, second hospital, etc. – implying there are several hospitals. I suggest changing "hospital" to "location" in each of these titles.
: {{Done}} Rusalkii (talk) 19:27, 18 March 2025 (UTC)
- Rename the last subsection of "History" to "Fourth location 1974–2015" and split the last two paragraphs of "History" into a new subsection, "Area expansion, since 2015".
: {{Done}} — 🌊PacificDepths (talk) 06:49, 12 May 2025 (UTC)
- In the penultimate paragraph of "History", delete
::Later that year, in October 2015, the expansion of the Brandywine Valley Specialty Care and Ambulatory Surgery Center was opened. This is a {{convert|44,000|sqft|m2|adj=on}} expansion.{{cite web|last1=Dyrda|first1=Laura|title=Children's Hospital of Philadelphia opens Brandywine Valley Specialty Care and ASC: 5 things to know|url=http://www.beckersasc.com/asc-transactions-and-valuation-issues/children-s-hospital-of-philadelphia-opens-brandywine-valley-specialty-care-and-asc-5-things-to-know.html|website=Beckersasc.com|access-date=2015-10-29|archive-date=2015-10-08|archive-url=https://web.archive.org/web/20151008150417/http://www.beckersasc.com/asc-transactions-and-valuation-issues/children-s-hospital-of-philadelphia-opens-brandywine-valley-specialty-care-and-asc-5-things-to-know.html|url-status=live}}
:This is a pretty minor expansion; mentioning it seems WP:UNDUE.
: {{Done}}, I don't have strong feelings either way. Rusalkii (talk) 19:27, 18 March 2025 (UTC)
- Add to end of "History":
::In January 2022, CHOP opened a new inpatient hospital on its King of Prussia campus,{{cite news |last1=Yu |first1=Alan |title=New children's hospital opens in King of Prussia |url=https://whyy.org/articles/new-childrens-hospital-opens-in-king-of-prussia/ |access-date=August 8, 2024 |work=WHYY |date=January 26, 2022}} followed by a new Center for Advanced Behavioral Healthcare in West Philadelphia in October 2022 and a Behavioral Health and Crisis Center in spring 2024.{{cite news |last1=Brubaker |first1=Harold |title=Philadelphia-area health systems had strong revenue growth for the first nine months of fiscal 2024 |url=https://www.inquirer.com/health/philadelphia-nonprofit-health-systems-financial-results-2024-nine-months-20240605.html |access-date=March 3, 2025 |work=The Philadelphia Inquirer |date=June 5, 2024 |language=en}}{{cite news |title=New CHOP Facility Expands Mental Health Crisis and Inpatient Care in Philadelphia |url=https://www.chop.edu/news/new-chop-facility-expands-mental-health-crisis-and-inpatient-care-philadelphia |access-date=March 3, 2025 |work=The Children's Hospital of Philadelphia |date=March 6, 2024 |language=en}} The hospital also opened new satellite locations in New Brunswick and Cape May, among others.{{cite news |last1=Toussaint |first1=Jensen |title=Children's Hospital of Philadelphia Continues To Thrive Under Madeline Bell's Leadership |url=https://philadelphia.today/2024/05/madeline-bell-chop/ |access-date=August 7, 2024 |work=PHILADELPHIA.Today |date=May 18, 2024}}
: {{Done}} — 🌊PacificDepths (talk) 06:49, 12 May 2025 (UTC)
- In "Facilities", update
::Each year the hospital admits more than 28,000 children and more than 1.167 million are seen in the emergency and outpatient departments.{{cite web|url=http://www.chop.edu/ar/pdf/Annual_Report_2010.pdf|title=Children's Hospital of Philadelphia 2010 – 11 Annual Report|year=2011|publisher=CHOP|archive-url=https://web.archive.org/web/20110427212220/http://www.chop.edu/ar/pdf/Annual_Report_2010.pdf|archive-date=April 27, 2011|access-date=June 9, 2012}}
:to
::Each year the hospital admits more than 34,000 patients and more than 1.6 million are seen in the emergency and outpatient departments. In addition to the facilities below, CHOP operates satellite locations in New Brunswick and Cape May, New Jersey, and Lancaster, Pennsylvania.{{cite news |last1=Bradley |first1=Michael |title=Madeline Bell Leads the Way at Children's Hospital of Philadelphia |url=https://mainlinetoday.com/life-style/madeline-bell/ |access-date=August 8, 2024 |work=Main Line Today |date=May 2, 2024}}
: {{Done}} — 🌊PacificDepths (talk) 06:49, 12 May 2025 (UTC)
- Add to end of "Expansion plans" in "Facilities":
::The second building, the Morgan Center for Research and Innovation, is a 17-story, 350,000-square-foot facility to provide more laboratory research capacity for molecular and biomedical studies. It began construction in 2022 and is scheduled to open in 2025.{{cite news |last1=Brubaker |first1=Harold |title=CHOP got a $50 million gift from Mitchell Morgan and his family for its new research building |url=https://www.inquirer.com/health/chop-mitchell-morgan-philadelphia-research-building-20240514.html |access-date=March 3, 2025 |work=The Philadelphia Inquirer |date=May 14, 2024 |language=en}}
: {{Done}} — 🌊PacificDepths (talk) 06:49, 12 May 2025 (UTC)
- Add new subsections to "Facilities":
::{{fake heading|sub=3|Center for Advanced Behavioral Health Care}}
::CHOP opened a mental health center in West Philadelphia in October 2022. The facility is located at at 46th and Market,{{cite news |last1=Stahl |first1=Stephanie |title=CHOP opens new mental health center in West Philadelphia |url=https://www.cbsnews.com/philadelphia/news/chop-opens-new-mental-health-center-in-west-philadelphia/ |access-date=August 8, 2024 |work=CBS Philadelphia |date=October 27, 2022}} with an address of 4601 Market St. The 47,000-square-foot facility was opened in response to rising demand due to gun violence and the COVID-19 pandemic, among other factors.{{cite news |last1=Gutman |first1=Abraham |title=CHOP has a new mental health center in West Philly. Community members want providers to spend time outside its walls. |url=https://www.inquirer.com/health/childrens-hospital-west-philadelphia-chop-behavioral-mental-health-20220826.html |access-date=August 8, 2024 |work=The Philadelphia Inquirer |date=August 26, 2022 |language=en}}{{cite news |last1=Larson |first1=Alec |title=CHOP opens behavioral health center in West Philly |url=https://www.phillytrib.com/news/local_news/chop-opens-behavioral-health-center-in-west-philly/article_4874f563-243a-5483-bec9-d49c9239a10b.html |access-date=August 8, 2024 |work=The Philadelphia Tribune |date=October 27, 2022 |language=en}}
::{{fake heading|sub=3|Behavioral Health and Crisis Center}}
::CHOP's Behavioral Health and Crisis Center, located on Cedar Avenue in West Philadelphia, is a pediatric inpatient behavioral health facility with a walk-in crisis center.
- Add to end of "Services":
::CHOP has also explored holistic treatment programs, particularly for mental health. In 2022, the hospital collaborated with Let’s Go Outdoors, Awbury Arboretum, and the U.S. Forest Service to create Prescribe Outside, a program encouraging children and their families to spend time outdoors as a form of preventative healthcare.{{cite news |last1=Adams |first1=Kiersten |title=Time in nature is a boon for children’s physical and mental health. It’s also great for parents |url=https://gridphilly.com/blog-home/2023/12/01/time-in-nature-is-a-boon-for-childrens-physical-and-mental-health-its-also-great-for-parents/ |access-date=August 21, 2024 |work=Grid Magazine |date=December 1, 2023}} This was a follow-up to a similar program, NaturePHL, launched in 2017.{{cite news |last1=Fisher |first1=Adjua |title=CHOP Docs Will Start Prescribing What This Summer? |url=https://www.phillymag.com/be-well-philly/2017/07/24/nature-prescriptions-chop/ |access-date=August 21, 2024 |work=Philadelphia Magazine |date=July 24, 2017}}{{cite news |last1=Weilbacher |first1=Mike |title=NATURAL SELECTIONS: CHOP’s Barbara Rolnick champions NaturePHL to fight ‘depression epidemic’ |url=https://www.timesherald.com/2016/12/09/natural-selections-chops-barbara-rolnick-champions-naturephl-to-fight-depression-epidemic/ |access-date=August 21, 2024 |work=The Times Herald |date=December 9, 2016}}
::CHOP is one of a few U.S. children's hospitals that can perform complicated fetal surgeries.{{cite news |last1=Holohan |first1=Meghan |title=EXCLUSIVE: 'Waiting for her to die': Baby with tumor on heart in the womb saved by rare surgery |url=https://www.today.com/health/health/fatal-pericardia-teratoma-fetal-heart-surgery-rcna178803 |access-date=January 14, 2025 |work=TODAY.com |date=November 6, 2024 |language=en}} The hospital established its Center for Fetal Diagnosis and Treatment in 1995;{{cite news |last1=Jones |first1=Ayana |title=CHOP performs 1,000th fetal surgery |url=https://www.phillytrib.com/sports/football/chop-performs-1-000th-fetal-surgery/article_797a20a4-dedf-5bf6-bb80-7156e2b6ebff.html |access-date=January 14, 2025 |work=The Philadelphia Tribune |date=June 11, 2013 |language=en}} in 2021, its 2,000th fetal surgery patient was born.{{cite news |last1=Romero |first1=Tracey |title=CHOP milestone exemplifies three decades of progress in fetal surgery |url=https://www.phillyvoice.com/chop-fetal-medicine-surgery-birth-defects-spina-bifida-/ |access-date=January 14, 2025 |work=PhillyVoice |date=June 22, 2021 |language=english}} CHOP also performs surgeries to separate conjoined twins.{{cite news |title=Twin boys born conjoined celebrate 1st birthday after separation surgery |url=https://apnews.com/article/conjoined-twins-separated-philadelphia-a95a93eea3482d6254a58e02fe605392 |access-date=January 14, 2025 |work=AP News |date=October 9, 2024 |language=en}} From 1957 to 2024, the hospital has completed 32 conjoined twin separations, more than any other North American hospital.{{cite news |last1=Lynch |first1=Cherise |title=CHOP surgeons successfully separate conjoined twin boys after 8-hour surgery |url=https://www.nbcphiladelphia.com/news/health/childrens-hospital-of-philadelphia-separates-conjoined-twin-boys-august-2024/3993340/ |access-date=January 14, 2025 |work=NBC10 Philadelphia |date=October 9, 2024}}
::The National Institutes of Health selected CHOP to join the Undiagnosed Diseases Network in 2018, providing research grants and including CHOP in a study on advanced genetic testing.{{cite news |last1=O'Brien |first1=Amanda |title=HUP and CHOP join Undiagnosed Diseases Network to study rare disorders |url=https://www.thedp.com/article/2018/10/hospital-of-university-pennsylvania-childrens-hospital-philadelphia-nih |access-date=January 14, 2025 |work=The Daily Pennsylvanian |date=October 1, 2018 |language=en-us}} CHOP has used an "ultra deep" type of genetic testing to support diagnosis of rare diseases.{{cite news |last1=Avril |first1=Tom |title=At CHOP, ‘ultra-deep’ genetic testing detects rare mutations that cause debilitating childhood diseases |url=https://www.inquirer.com/health/childrens-hospital-philadelphia-genetic-testing-lymphatic-vascular-medications-20230729.html |access-date=January 14, 2025 |work=The Philadelphia Inquirer |date=July 29, 2023 |language=en}}{{cite news |last1=Ellison |first1=Katherine |title=When a child is mysteriously and seriously ill, here are places to turn |url=https://www.washingtonpost.com/wellness/2024/08/05/children-rare-diseases-undiagnosed-network/ |access-date=January 14, 2025 |work=Washington Post |date=August 5, 2024 |language=en}} The Advanced Research Projects Agency for Health gave CHOP a $10 million grant in October 2024 to implement Real-time Analysis and Discovery in Integrated And Networked Technologies (RADIANT), a tool to gather and share data on rare childhood diseases from electronic health records of patients around the U.S. in real time.{{cite news |last1=McCook |first1=Alison |title=CHOP gets $10 million for tool to transform care for kids with rare diseases |url=https://www.inquirer.com/health/chop-cancer-arpa-h-radiant-20241016.html |access-date=January 14, 2025 |work=The Philadelphia Inquirer |date=October 16, 2024 |language=en}}
::{{As of|2024|06}}, CHOP was running 11 remote management programs with capacity to monitor 11,000 patients, a tactic that is usually more common in adult than pediatric care.{{cite news |last1=Bruce |first1=Giles |title=How 1 hospital bucked a remote patient monitoring trend |url=https://www.beckershospitalreview.com/innovation/how-1-hospital-bucked-a-remote-patient-monitoring-trend.html |access-date=January 14, 2025 |work=Becker's Hospital Review |date=June 13, 2024 |language=en-gb}}
- Add to end of "Research" (which should maybe be a top-level section?):
::CHOP led the 2011 Management of Myelomeningocele Study, which was first to demonstrate that fetal surgery for spina bifida could offer more benefits than repair after birth. CHOP also participated in a follow-up study, conducted between 2011 and 2017 and published in 2021, that confirmed the benefits continued into patients' school years.{{cite news |last1=Gantz |first1=Sarah |title=Children’s Hospital of Philadelphia finds benefits of fetal surgery for spina bifida continue years later |url=https://www.inquirer.com/health/spina-bifida-study-chop-20200124.html |access-date=January 14, 2025 |work=The Philadelphia Inquirer |date=January 24, 2020 |language=en}}
::In 2016, CHOP's Center for Autism Research joined the Simons Foundation Autism Research Initiative's study on genetics and autism,{{cite news |last1=George |first1=John |title=CHOP joins 'largest ever' autism genetics study |url=https://www.bizjournals.com/philadelphia/morning_roundup/2016/04/chop-joins-largest-ever-autism-genetics-study.html |access-date=August 8, 2024 |work=Philadelphia Business Journal |date=April 29, 2016}} the largest autism study in the history of the U.S.{{cite news |last1=Craig |first1=Daniel |title=CHOP joining country's largest autism study |url=https://www.phillyvoice.com/chop-joining-countrys-largest-autism-study/ |access-date=August 8, 2024 |work=PhillyVoice |date=April 29, 2016 |language=english}}
::Several CHOP doctors published a 2021 study in the Journal of the American Academy of Child and Adolescent Psychiatry comparing rates of attempted suicide among Black American pre-adolescent and their white peers, linking the increase for Black youths to exposure to discrimination.{{cite news |last1=Gutman |first1=Abraham |title=CHOP's only psychiatrist for infants is worried about the mental health of Philadelphia's youngest |url=https://www.inquirer.com/health/child-mental-health-chop-racism-20220621.html |access-date=August 21, 2024 |work=The Philadelphia Inquirer |date=June 21, 2022 |language=en}}{{cite journal|doi=10.1016/j.jaac.2021.08.011 |date=2022 |volume=61 |issue=5 |last1=Argabright |first1=Stirling T. |last2=Visoki |first2=Elina |last3=Moore |first3=Tyler M. |last4=Ryan |first4=Dallas T. |last5=DiDomenico |first5=Grace E. |last6=Njoroge |first6=Wanjikũ F.M. |last7=Taylor |first7=Jerome H. |last8=Guloksuz |first8=Sinan |last9=Gur |first9=Ruben C. |last10=Gur |first10=Raquel E. |last11=Benton |first11=Tami D. |last12=Barzilay |first12=Ran |title=Association Between Discrimination Stress and Suicidality in Preadolescent Children |journal=Journal of the American Academy of Child & Adolescent Psychiatry |pages=686–697 |pmid=34425231 |pmc=8917360 }}
- Add a subsection to "Research":
::{{fake heading|sub=3|Cell and gene therapies}}
::In 2012, CHOP treated a child with leukemia using CAR T cell therapy, making her the first child cured of cancer using this therapy.{{cite news |last1=Gantz |first1=Sarah |title=Emily Whitehead was the first child cured of cancer with therapy from Penn. She's back as a freshman. |url=https://www.inquirer.com/health/leukemia-treatment-chop-emily-whitehead-upenn-20231030.html |access-date=August 8, 2024 |work=The Philadelphia Inquirer |date=October 30, 2023 |language=en}}
::From 2008 to 2018, CHOP participated in 30 clinical trials for cell and gene therapies, creating products for hundreds of patients. In October 2018, CHOP opened a 15,000-square-foot, $75 million clinical manufacturing facility focused on testing cell and gene therapies and producing viral vectors to deliver them.{{cite news |last1=George |first1=John |title=Gene therapy: CHOP unveils $75M manufacturing facility (Photos) |url=https://www.bizjournals.com/philadelphia/news/2018/11/01/gene-therapy-chop-unveils-75m-manufacturing.html |access-date=August 21, 2024 |work=Philadelphia Business Journal |date=November 1, 2018}} The facility more than doubles the hospital's production capacity and reduces cost per treatment. The facility is located in the basement of the Colket Translational Research Building in University City.{{cite news |last1=DiStefano |first1=Joseph N. |title=CHOP set to open its gene-therapy factory |url=https://www.inquirer.com/philly/blogs/inq-phillydeals/chop-set-to-open-its-gene-therapy-factory-20181101.html |access-date=August 21, 2024 |work=The Philadelphia Inquirer |date=November 1, 2018 |language=en}} The next year, CHOP scientists announced in Nature Communications that they had developed a sensitive screening method for adeno-associated virus vectors.{{cite news |title=Gene Therapy Vectors Deliver to More Places Than Once Thought |url=https://www.genengnews.com/topics/genome-editing/gene-therapy-vectors-deliver-to-more-places-than-once-thought/ |access-date=August 22, 2024 |work=GEN - Genetic Engineering and Biotechnology News |date=July 31, 2019}}
::In 2021, CHOP conducted a study on Casgevy, a gene therapy treatment using CRISPR to treat sickle cell disease. Casgevy received FDA approval in December 2023, making it the first gene therapy to treat sickle cell disease approved by the Food and Drug Administration.{{cite news |last1=Avril |first1=Tom |title=The FDA just approved the first gene-editing treatment, and CHOP played a key role |url=https://www.inquirer.com/health/crispr-sickle-cell-chop-vertex-20231208.html |access-date=August 21, 2024 |work=The Philadelphia Inquirer |date=December 8, 2023 |language=en}} By August 2024, CHOP had provided gene therapy to its first sickle cell patient outside of a research setting.{{cite news |last1=Stahl |first1=Stephanie |last2=Nau |first2=Brad |title=New Jersey college student suffering from sickle cell disease has newfound hope with gene therapy at CHOP - CBS Philadelphia |url=https://www.cbsnews.com/philadelphia/news/sickle-cell-disease-childrens-hospital-of-philadelphia/ |access-date=January 14, 2025 |work=CBS Philadelphia |date=September 11, 2024}}
::CHOP research also played a role in the development of two other FDA-approved gene therapies, Kymriah for leukemia (approved in August 2017{{cite news |last1=Schweigert |first1=Keith |title=FDA approves new gene therapy treatment for leukemia developed by Penn Medicine and CHOP |url=https://www.fox43.com/article/news/local/contests/fda-approves-new-gene-therapy-treatment-for-leukemia-developed-by-penn-medicine-and-chop/521-12f39285-08b9-4cef-90d2-71f3b3bbe6ad |access-date=August 21, 2024 |work=FOX43 |date=August 31, 2017}}) and Luxturna for an inherited blindness (approved in December 2017{{cite news |last1=McGinley |first1=Laurie |title=FDA approves first gene therapy for an inherited disease |url=https://www.washingtonpost.com/news/to-your-health/wp/2017/12/18/fda-approves-first-gene-therapy-for-an-inherited-disease-childhood-blindness/ |access-date=August 21, 2024 |work=Washington Post |date=October 26, 2021}}). Luxturna is produced by Spark Therapeutics, which spun off from CHOP in 2013.
::In 2023, the hospital acquired a machine to support the production of CAR T cell therapies faster and at lower cost.{{cite news |last1=Scott |first1=Maiken |title=CHOP's on-site production could lower high cost of gene therapies |url=https://whyy.org/segments/chops-on-site-production-could-lower-high-cost-of-gene-therapies/ |access-date=August 8, 2024 |work=WHYY |date=November 27, 2023}} By November 2023, CHOP had treated more than 500 children and hundreds more adults with CAR T therapy.{{cite news |last1=Gantz |first1=Sarah |title=FDA is investigating whether CAR-T, a cancer therapy pioneered at Penn, can cause lymphoma |url=https://www.inquirer.com/health/fda-investigation-gene-therapy-cancer-claims-20231128.html |access-date=August 8, 2024 |work=The Philadelphia Inquirer |date=November 28, 2023 |language=en}} The hospital conducted research finding that children with acute lymphoblastic leukemia from low-income households receive similar benefit from these therapies as children from more advantaged households.{{cite news |title=CAR T-Cell Therapy Performs Just as Well in Low-Income Kids as in Wealthier Kids |url=https://www.insideprecisionmedicine.com/news-and-features/car-t-cell-therapy-performs-just-as-well-in-poor-as-in-wealthier-kids/ |access-date=August 8, 2024 |work=Inside Precision Medicine |date=November 16, 2022}} CHOP has also collaborated with the Stanford University School of Medicine on research explaining how CAR T therapies work and how to improve them.{{cite news |title=CAR T Cell Therapies Last Longer, Work Better with FOXO1 Protein |url=https://www.genengnews.com/topics/cancer/car-t-cell-therapies-last-longer-work-better-with-foxo1-protein/ |access-date=August 8, 2024 |work=GEN - Genetic Engineering and Biotechnology News |date=April 11, 2024}}
::In January 2024, CHOP announced that it had allowed an 11-year-old boy who was born deaf in both ears due to the OTOF gene{{cite news |last1=Cohen |first1=Jessica Kim |title=Young Boy Can Hear After Receiving Eli Lilly's Gene Therapy, Bolstering Similar Programs |url=https://www.precisionmedicineonline.com/business-news/young-boy-can-hear-after-receiving-eli-lillys-gene-therapy-bolstering-similar |access-date=August 22, 2024 |work=Precision Medicine Online |date=January 25, 2024}} to hear for the first time using an experimental gene therapy treatment, marking the first time gene therapy was used as a treatment for hereditary hearing loss in the U.S.{{cite news |last1=Grassi |first1=Emily Rose |title=Boy born deaf can hear for the first time thanks to ground-breaking gene therapy |url=https://www.nbcphiladelphia.com/news/health/chop-genetic-hearing-loss-gene-therapy/3755700/ |access-date=August 8, 2024 |work=NBC10 Philadelphia |date=January 24, 2024}}
- In "Awards", add after (or replace?) "In 2021 the hospital was ranked as the No. 2 best children's hospital in the United States by U.S. News & World Report on the publications' honor roll list.{{Cite web|last=Harder|first=Ben|date=16 June 2020|title=The Honor Roll of U.S. News Best Children's Hospitals 2020-21|url=https://health.usnews.com/health-news/best-childrens-hospitals/slideshows/best-childrens-hospitals-honor-roll|access-date=16 June 2020|website=U.S. News & World Report|archive-date=16 June 2020|archive-url=https://web.archive.org/web/20200616112455/https://health.usnews.com/health-news/best-childrens-hospitals/slideshows/best-childrens-hospitals-honor-roll|url-status=live}}":
::In its 2024–2025 rankings, U.S. News & World Report included CHOP on its unranked "honor roll" of the best children's hospitals{{cite news |last1=Harder |first1=Ben |title=Best Children's Hospitals 2024-2025 Honor Roll and Overview |url=https://health.usnews.com/health-news/best-childrens-hospitals/articles/best-childrens-hospitals-honor-roll-and-overview |access-date=March 3, 2025 |work=US News & World Report |date=October 8, 2024 |language=en}} and named it the #1 children's hospital in the Mid-Atlantic region.{{cite web |title=Children's Hospital of Philadelphia |url=https://health.usnews.com/best-hospitals/area/pa/childrens-hospital-of-philadelphia-6231730 |access-date=March 3, 2025 |work=U.S. News & World Report}}
- In "Awards", update
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: {{Done}}, not convinced this table should exist but given that it does updated is better than out of date. Rusalkii (talk) 19:30, 18 March 2025 (UTC)
{{sources-talk}}
I know there's a lot here, so let me know if it makes more sense to break these out into separate items or if there's anything else I can do to make this easier to review. Thank you for your time! Mary Gaulke (talk) 21:00, 5 March 2025 (UTC)
:Partly done. May return to this later, may not; other editors should feel free to take over. Rusalkii (talk) 19:30, 18 March 2025 (UTC)