Α-Methylhistamine

{{lowercase title}}

{{Chembox

| Verifiedfields = changed

| Watchedfields = changed

| verifiedrevid = 477319463

| Name = α-Methylhistamine

| ImageFile = Alpha-Methylhistamine.svg

| ImageFile_Ref = {{chemboximage|correct|??}}

| ImageSize = 244

| ImageName = Skeletal formula of a minor tautomer of alpha-methylhistamine

| IUPACName = 1-(3H-Imidazol-4-yl)propan-2-amine

| SystematicName = 1-(1H-Imidazol-4-yl)propan-2-amine{{Cite web|url=https://www.ebi.ac.uk/chebi/searchId.do?chebiId=295965|title=Chemical Entities of Biological Interest (ChEBI)}}

|Section1={{Chembox Identifiers

| CASNo = 6986-90-9

| CASNo_Ref = {{cascite|changed|??}}

| CASNo1 = 75614-87-8

| CASNo1_Ref = {{cascite|correct|CAS}}

| CASNo1_Comment = (R)

| CASNo2 = 75614-93-6

| CASNo2_Ref = {{cascite|correct|CAS}}

| CASNo2_Comment = (S)

| PubChem = 3615

| PubChem1 = 156615

| PubChem1_Comment = (R)

| PubChem2 = 6603865

| PubChem2_Comment = (S)

| ChemSpiderID = 3489

| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}

| MeSHName = Alpha-methylhistamine

| ChEBI_Ref = {{ebicite|changed|EBI}}

| ChEBI = 295965

| ChEMBL = 116655

| ChEMBL_Ref = {{ebicite|correct|EBI}}

| IUPHAR_ligand = 1239

| SMILES = CC(N)CC1=CNC=N1

| StdInChI = 1S/C6H11N3/c1-5(7)2-6-3-8-4-9-6/h3-5H,2,7H2,1H3,(H,8,9)

| StdInChI_Ref = {{stdinchicite|correct|chemspider}}

| InChI = 1/C6H11N3/c1-5(7)2-6-3-8-4-9-6/h3-5H,2,7H2,1H3,(H,8,9)

| StdInChIKey = XNQIOISZPFVUFG-UHFFFAOYSA-N

| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}

| InChIKey = XNQIOISZPFVUFG-UHFFFAOYAW

}}

|Section2={{Chembox Properties

| C=6 | H=11 | N=3

| LogP = −0.346

}}

}}

α-Methylhistamine is a histamine agonist selective for the receptor subtype H₃. It causes lowering of blood pressure and a decrease of heart rate in animal models.{{cite journal|title=Production by R-alpha-methylhistamine of a histamine H3 receptor-mediated decrease in basal vascular resistance in guinea-pigs|journal=Br J Pharmacol|volume=110|issue=2|pages=553–558|pmid=7902173|year=1993|last1=McLeod|first1=RL|last2=Gertner|first2=SB|last3=Hey|first3=JA|pmc=2175947|doi=10.1111/j.1476-5381.1993.tb13846.x}}