1-Benzyl-4-(2-(diphenylmethoxy)ethyl)piperidine

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| Verifiedfields = changed

| verifiedrevid = 477207047

| ImageFile = 1-Benzyl-4-(2-(diphenylmethoxy)ethyl)piperidine.svg

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| Name = 1-Benzyl-4-[2-(diphenylmethoxy){{SHY}}ethyl]piperidine

| PIN = 1-Benzyl-4-[2-(diphenylmethoxy){{SHY}}ethyl]piperidine

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|Section1={{Chembox Identifiers

| CASNo = 174643-75-5

| CASNo_Ref = {{cascite|changed|??}}

| SMILES = O(C(c1ccccc1)c2ccccc2)CCC4CCN(Cc3ccccc3)CC4

| InChI = 1/C27H31NO/c1-4-10-24(11-5-1)22-28-19-16-23(17-20-28)18-21-29-27(25-12-6-2-7-13-25)26-14-8-3-9-15-26/h1-15,23,27H,16-22H2

| InChIKey = WRSJONWBAYSODC-UHFFFAOYAC

| ChEMBL_Ref = {{ebicite|correct|EBI}}

| ChEMBL = 338733

| StdInChI_Ref = {{stdinchicite|correct|chemspider}}

| StdInChI = 1S/C27H31NO/c1-4-10-24(11-5-1)22-28-19-16-23(17-20-28)18-21-29-27(25-12-6-2-7-13-25)26-14-8-3-9-15-26/h1-15,23,27H,16-22H2

| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}

| StdInChIKey = WRSJONWBAYSODC-UHFFFAOYSA-N

| PubChem = 9952105

| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}

| ChemSpiderID = 8127716

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|Section2={{Chembox Properties

| C=27 | H=31 | N=1 | O=1

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1-Benzyl-4-[2-(diphenyl{{wbr}}methoxy){{wbr}}ethyl]{{wbr}}piperidine is a stimulant of the piperidine class which acts as a potent and selective dopamine reuptake inhibitor.{{cite journal |vauthors=Dutta AK, Coffey LL, Reith ME | title = Highly selective, novel analogs of 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine for the dopamine transporter: effect of different aromatic substitutions on their affinity and selectivity | journal = Journal of Medicinal Chemistry | volume = 40 | issue = 1 | pages = 35–43 |date=January 1997| pmid = 9016326 | doi = 10.1021/jm960638e }}{{cite journal |vauthors=Dutta AK, Davis MC, Fei XS, Beardsley PM, Cook CD, Reith ME | title = Expansion of structure-activity studies of piperidine analogues of 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine (GBR 12935) compounds by altering substitutions in the N-benzyl moiety and behavioral pharmacology of selected molecules | journal = Journal of Medicinal Chemistry | volume = 45 | issue = 3 | pages = 654–62 |date=January 2002| pmid = 11806716| doi = 10.1021/jm010316x}} It is closely related to vanoxerine and GBR-12,935, which in contrast are piperazines.

See also

References

{{Reflist}}

{{Stimulants}}

{{Dopaminergics}}

{{DEFAULTSORT:Benzyl-4-(2-(diphenylmethoxy)ethyl)piperidine, 1-}}

Category:Piperidines

Category:Stimulants

Category:Benzyl compounds