1522 in literature

• September 21 – Luther Bible: Martin Luther's translation of the Bible's New Testament into Early New High German from Greek, Das newe Testament Deutzsch, is published in Germany, selling thousands in the first few weeks.
• Luo Guanzhong's 14th-century compilation Romance of the Three Kingdoms is first printed, as Sanguozhi Tongsu Yanyi.

File:Gutenberg Bible.jpg]]

• Desiderius Erasmus – Novum Testamentum (Greek Textus Receptus of the New Testament, third edition)
• Martin Luther – Against Henry, King of the English (Contra Henricum Regem Anglie)
• Adam Ries – {{lang|de|Rechenung auff der Linihen und Federn}}

• Niklaus Manuel Deutsch I – Vom Papst und Christi Gegensatz
• The World and the Child (Mundus et Infans, published)

{{main|1522 in poetry}}

• Thomas Murner – Von dem grossen Lutherischen Narren ("Of the Great Lutheran Fool"){{cite book|last=Thomas|first=Calvin|url=https://archive.org/details/bub_gb_n9EPAAAAMAAJ|quote=German literature.|title=A History of German Literature|location=New York|publisher=D. Appleton & Co|year=1909|accessdate=2009-12-14}}

• February – Jean de Nostredame, Provençal historian (died c.1576)
• June 1 – Dirck Volckertszoon Coornhert, Dutch classical scholar (died 1590)
• unknown dates
• Joachim du Bellay, French poet (died 1560){{cite book|author1=Harry G. Lang|author2=Harry G Lang|author3=Bonnie Meath-Lang|title=Deaf Persons in the Arts and Sciences: A Biographical Dictionary|url=https://books.google.com/books?id=6OaPbpdmxEgC&pg=PA98|year=1995|publisher=Greenwood Publishing Group|isbn=978-0-313-29170-8|pages=98}}
• Siôn Tudur, Welsh poet (died 1602)

• January 25 – Raffaello Maffei, Italian humanist historian and theologian (born 1451){{cite book|author1=Peter G. Bietenholz|author2=Thomas Brian Deutscher|title=Contemporaries of Erasmus: A Biographical Register of the Renaissance and Reformation|url=https://books.google.com/books?id=hruQ386SfFcC&pg=RA1-PA366|date=1 January 2003|publisher=University of Toronto Press|isbn=978-0-8020-8577-1|pages=366}}
• February 25 – William Lilye, English classical scholar (born c. 1468)
• June 30 – Johann Reuchlin, German humanist scholar and poet (born 1455)
• September – Gavin Douglas, Scottish poet and bishop (born c. 1474){{cite book|author1=Arthur F. Kinney|author2=David W. Swain|author3=Eugene D. Hill|author4=William A. Long|title=Tudor England: An Encyclopedia|url=https://books.google.com/books?id=nHasAgAAQBAJ&pg=PA200|date=17 November 2000|publisher=Routledge|isbn=978-1-136-74530-0|pages=200}}

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{{Year in literature article categories}}