1954 Challenge Desgrange-Colombo

{{ Infobox cycling season

| name = 1954 Challenge Desgrange-Colombo

| edition = 7

| competition = Challenge Desgrange-Colombo

| image =

| image_caption =

| image_alt =

| image_size =

| dates = 19 March – 31 October

| location = Europe

| rounds = 11

| individual_champion = {{flagathlete|Ferdinand Kübler|SUI}}

| individual_champion_team = Fiorelli

| nations_champion = {{flagu|Belgium}}

| previous = 1953

| next = 1955

}}

The 1954 Challenge Desgrange-Colombo was the seventh edition of the Challenge Desgrange-Colombo. It included eleven races: all the races form the 1953 edition were retained with no additions. Ferdinand Kübler won his third individual championship (although he did not win any of the races) while Belgium won the nations championship.