1P-ETH-LAD

{{short description|Chemical compound}}

{{Drugbox

|IUPAC_name=(6aR,9R)-N,N-Diethyl-7-ethyl-4-propanoyl-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-9-carboxamide

|image=1P-ETH-LAD Structural Formulae V2.svg

|width=150px

|tradename=

|legal_AU=

|legal_CA=

|legal_DE = NpSG

|legal_UK=PSA

|legal_US=

|legal_status= Illegal in France{{cite web|date=20 May 2021|title=Arrêté du 20 mai 2021 modifiant l'arrêté du 22 février 1990 fixant la liste des substances classées comme stupéfiants|url=https://www.legifrance.gouv.fr/jorf/id/JORFTEXT000043523554|website=www.legifrance.gouv.fr|lang=fr}}

|routes_of_administration=Oral

|metabolism=Hepatic

|excretion=Renal

|CAS_number_Ref={{cascite|changed|??}}

|CAS_number=2230715-45-2

|PubChem=119025859

|ChemSpiderID_Ref={{chemspidercite|correct|chemspider}}

|ChemSpiderID=52085137

|ChEMBL_Ref={{ebicite|correct|EBI}}

|ChEMBL=|UNII_Ref={{fdacite|changed|FDA}}

|UNII=HA76076A0R

|synonyms=

|C=24|H=31|N=3|O=2

|smiles=CCC(=O)N1C=C2C[C@@H]3C(=C[C@H](CN3CC)C(=O)N(CC)CC)C4=C2C1=CC=C4

|StdInChI_Ref={{stdinchicite|correct|chemspider}}|StdInChI=1S/C24H31N3O2/c1-5-22(28)27-15-16-13-21-19(18-10-9-11-20(27)23(16)18)12-17(14-26(21)8-4)24(29)25(6-2)7-3/h9-12,15,17,21H,5-8,13-14H2,1-4H3/t17-,21-/m1/s1

|StdInChIKey_Ref={{stdinchicite|correct|chemspider}}

|StdInChIKey=MLOFCBXSOAYCIF-DYESRHJHSA-N

}}

1P-ETH-LAD (1-propionyl-6-ethyl-6-nor-lysergic acid diethylamide) is an analog of LSD. 1P-ETH-LAD is a psychedelic drug similar to LSD. Research has shown formation of ETH-LAD from 1P-ETH-LAD incubated in human serum, suggesting that it functions as a prodrug.{{cite journal | vauthors = Brandt SD, Kavanagh PV, Westphal F, Elliott SP, Wallach J, Stratford A, Nichols DE, Halberstadt AL | display-authors = 6 | title = 6 -ethyl-6-norlysergic acid diethylamide (ETH-LAD) and 1-propionyl ETH-LAD (1P-ETH-LAD) | journal = Drug Testing and Analysis | volume = 9 | issue = 10 | pages = 1641–1649 | date = October 2017 | pmid = 28342178 | pmc = 6230477 | doi = 10.1002/dta.2196 }} It is part of the lysergamide chemical class. Like ETH-LAD, this drug has been reported to be significantly more potent than LSD itself, and is reported to largely mimic ETH-LAD's psychedelic effects.{{citation needed|date=November 2020}}

1P-ETH-LAD has little history of human usage before January 2016.