2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase

{{Short description|Class of enzymes}}

{{infobox enzyme

| Name = 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase

| EC_number = 1.3.1.58

| CAS_number =

| GO_code = 0018511

| image =

| width =

| caption =

}}

In enzymology, a 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase ({{EC number|1.3.1.58}}) is an enzyme that catalyzes the chemical reaction

:cis-5,6-dihydroxy-4-isopropylcyclohexa-1,3-dienecarboxylate + NAD+ \rightleftharpoons 2,3-dihydroxy-p-cumate + NADH + H+

Thus, the two substrates of this enzyme are cis-5,6-dihydroxy-4-isopropylcyclohexa-1,3-dienecarboxylate and NAD+, whereas its 3 products are 2,3-dihydroxy-p-cumate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cis-2,3-dihydroxy-2,3-dihydro-p-cumate:NAD+ oxidoreductase. This enzyme participates in biphenyl degradation.

References

{{reflist|1}}

  • {{cite journal | vauthors = Eaton RW | title = p-Cumate catabolic pathway in Pseudomonas putida Fl: cloning and characterization of DNA carrying the cmt operon | journal = Journal of Bacteriology | volume = 178 | issue = 5 | pages = 1351–62 | date = March 1996 | pmid = 8631713 | pmc = 177810 }}

{{CH-CH oxidoreductases}}

{{Enzymes}}

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Category:EC 1.3.1

Category:NADH-dependent enzymes

Category:Enzymes of unknown structure

{{1.3-enzyme-stub}}