2-Ethoxyethanol

{{chembox

|Verifiedfields = changed

|Watchedfields = changed

|verifiedrevid = 477213258

|Name = 2-Ethoxyethanol

|ImageFile = 2-Ethoxyethanol2.svg

|ImageName = 2-Ethoxyethanol

|PIN = 2-Ethoxyethanol

|OtherNames = Cellosolve
ethylene glycol ethyl ether
oxitol
Ethyl Cellosolve
EGEE

|Section1={{Chembox Identifiers

|DrugBank_Ref = {{drugbankcite|correct|drugbank}}

|DrugBank = DB02249

|ChEBI_Ref = {{ebicite|correct|EBI}}

|ChEBI = 46788

|KEGG_Ref = {{keggcite|correct|kegg}}

|KEGG = C14687

|PubChem = 8076

|ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}

|ChemSpiderID = 13836591

|EC_number = 203-804-1

|UNNumber = 1171

|Beilstein = 1098271

|Gmelin = 82142

|SMILES = CCOCCO

|InChI = 1/C4H10O2/c1-2-6-4-3-5/h5H,2-4H2,1H3

|InChIKey = ZNQVEEAIQZEUHB-UHFFFAOYAD

|StdInChI = 1S/C4H10O2/c1-2-6-4-3-5/h5H,2-4H2,1H3

|StdInChIKey = ZNQVEEAIQZEUHB-UHFFFAOYSA-N

|ChEMBL_Ref = {{ebicite|correct|EBI}}

|ChEMBL = 119596

|UNII_Ref = {{fdacite|correct|FDA}}

|UNII = IDK7C2HS09

|CASNo_Ref = {{cascite|correct|CAS}}

|CASNo = 110-80-5

|RTECS = KK8050000

}}

|Section2={{Chembox Properties

|C=4 | H=10 | O=2

|Appearance = clear liquid

|Odor = sweet, ether-like

|Density = 0.930 g/cm3, liquid

|Solubility = miscible

|MeltingPtC = -70

|BoilingPtC = 135

|VaporPressure = 4 mmHg (20°C)

}}

|Section7={{Chembox Hazards

|NFPA-H = 2

|NFPA-F = 2

|NFPA-R =

|FlashPtC = 44

|GHSPictograms = {{GHS02}}{{GHS06}}{{GHS07}}{{GHS08}}

|GHSSignalWord = Danger

|HPhrases = {{H-phrases|226|302|331|360}}

|PPhrases = {{P-phrases|201|202|210|233|240|241|242|243|261|264|270|271|280|281|301+312|303+361+353|304+340|308+313|311|321|330|370+378|403+233|403+235|405|501}}

|PEL = TWA 200 ppm (740 mg/m3) [skin]{{PGCH|0258}}

|ExploLimits = 1.7–15.6%

|IDLH = 500 ppm

|REL = TWA 0.5 ppm (1.8 mg/m3) [skin]

|LC50 = 2000 ppm (rat, 7 hr)
1820 ppm (mouse, 7 hr){{IDLH|110805|2-Ethoxyethanol}}

|LD50 = 2451 mg/kg (mouse, oral)
2125 mg/kg (rat, oral)

|LCLo = 3000 ppm (guinea pig, 24 hr)

}}

|Section8={{Chembox Related

|OtherFunction_label = ethers

|OtherFunction = 2-Propoxyethanol
2-Butoxyethanol

|OtherCompounds = Ethylene glycol

}}

}}

2-Ethoxyethanol, also known by the trademark Ethyl cellosolve, is a solvent used widely in commercial and industrial applications. It is a clear, colorless, nearly odorless liquid that is miscible with water, ethanol, diethyl ether, acetone, and ethyl acetate.{{cite book|author=National Research Council (U.S.). Subcommittee on Spacecraft Maximum Allowable Concentrations|title=Spacecraft maximum allowable concentrations for selected airborne contaminants|url=https://books.google.com/books?id=3VZRtLk--BAC&pg=PT210|access-date=19 February 2012|year=1996|publisher=National Academies Press|isbn=978-0-309-05478-2|page=189}}

2-Ethoxyethanol is manufactured by the reaction of ethylene oxide with ethanol.

As with other glycol ethers, 2-ethoxyethanol has the useful property of being able to dissolve chemically diverse compounds. It will dissolve oils, resins, grease, waxes, nitrocellulose, and lacquers. This is an ideal property as a multi-purpose cleaner, and, therefore, 2-ethoxyethanol is used in products such as varnish removers and degreasing solutions.

References